Indiana University-Purdue University Indianapolis (IUPUI) researchers in the Department of Chemistry & Chemical Biology have developed a new procedure for the synthesis of 鈥渜uantum dots,鈥� as published March 31, 2006 on the Chemistry of Materials website.

Quantum dots are highly fluorescent nanoscale-sized solid particles that are finding increasing applications as imaging probes in the burgeoning field of nanomedicine. Due to their sheer brightness and high photostability, quantum dots have the ability to act as molecular 鈥渂eacons.鈥� When attached to compounds or proteins of interest, quantum dots allow researchers to track movements within biological media or whole organisms, significantly impacting the way medical professionals study, diagnose and treat diseases.

The work of IUPUI researchers will make quantum dot technology more accessible.

According to Naumann and Long, faculty within the Department of Chemistry & Chemical Biology, and article co-authors, quantum dot materials are costly and inconvenient for biomedical laboratories, as synthesis requires high-temperature techniques. The new synthesis developed at IUPUI makes use of room temperature sonochemistry to generate quantum dots that span the full range of colors in the visible spectrum.

鈥淭his new, low temperature procedure may also facilitate the large-scale synthesis of quantum dots and allow inclusion of temperature sensitive materials in the synthesis procedure itself,鈥� they said.

鈥淭his is very exciting research鈥攖he kind of research that will lead to improvements in medical diagnosis and to further breakthroughs in fundamental science,鈥� said Carl Cowen, dean of the IUPUI School of Science. 鈥淭his announcement is one of many we have seen and will continue to see from biomaterials researchers of the IUPUI Department of Chemistry & Chemical Biology.鈥�

Citation: 鈥淔acile Sonochemical Synthesis of Highly Luminescent ZnS-Shelled CdSe Quantum Dots鈥� M. J. Murcia, D. L. Shaw, H. Woodruff, C. A. Naumann, B. A. Young & E. C. Long:

Source: Indiana University-Purdue University Indianapolis