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January 14, 2025

Team develops plan for 3D-printed microscope, including lens, that costs less than $60

An exploded view of a fully 3D printed microscope. Credit: Biophysics (2024). DOI: 10.1101/2024.12.16.628684
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An exploded view of a fully 3D printed microscope. Credit: Biophysics (2024). DOI: 10.1101/2024.12.16.628684

A team of physicists and engineers at the University of Strathclyde, in Scotland, working with a colleague from the University of Glasgow, has developed the means for 3D printing a microscope, including the lens, for under $60. In their posted on the bioRxiv preprint server, the group describes how they came up with the plans for the microscope and notes that the end result has a resolution strong enough to make out individual blood cells in test samples.

The cost of high-resolution microscopes can be prohibitively high for millions of students and researchers around the world. In this new study, the researchers in Scotland have developed plans, available for free online, that can be used to 3D-print a fully functional, high-resolution microscope.

The plans for producing the main structure of the microscope and its associated components, the researchers note, have been available for a while, courtesy of the . The trick was to find a way to 3D-print the lenses—typically, they are produced in high-precision factories, resulting in high costs.

The team started experimenting with 3D-printed lenses and found it was possible to print quality microscope lenses using a photopolymerizing clear resin on a Mars 3 Pro printer. In developing the specifications for their lenses, they followed those of the Edmund Optics 12.7 mm diameter plano-convex , which has a of 35 mm.

The plans call for printing the microscope as a series of parts, including the lenses, which are then assembled to build a completely functional microscope. During testing of the , the research team added an off-the-shelf light source and camera, which was controlled by a Raspberry Pi processor. Even with the additional components, the researchers note, the entire setup cost less than $60 and took less than three hours to create.

More information: Jay Christopher et al, A fully 3D-printed optical microscope for low-cost histological imaging, bioRxiv (2024).

Journal information: bioRxiv

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Âé¶¹ÒùÔºicists and engineers have developed a method to 3D-print a microscope, including the lens, for under $60. The design, available online, allows for the creation of a high-resolution microscope capable of resolving individual blood cells. The innovation lies in 3D-printing the lenses using a photopolymerizing resin, following specifications of a standard plano-convex lens. The complete setup, including additional components, is affordable and quick to assemble.

This summary was automatically generated using LLM.