Could forensic scientists soon reconstruct facial 3D images from DNA at crime scenes?
In research published in , investigators describe their ability to reconstruct 3D facial images from DNA data, which could have important applications in forensic investigations of crime scenes.
Their model, called Difface, applies single DNA nucleotide differences to 3D facial point clouds, or sets of data points that represent the exterior surface of a face.
When tested on a Han Chinese database with 9,674 paired DNA differences and 3D facial images, Difface demonstrated excellent performance in DNA-to-3D image alignment and reconstruction. Also, including additional information such as age, sex, and body mass index in Difface further improved the quality of reconstructed facial 3D images.
"Amazingly, Difface could generate 3D facial images of individuals solely from their DNA data, projecting their appearance at various future ages," said co–corresponding author Luonan Chen, Ph.D., of the Chinese Academy of Sciences.
More information: De novo reconstruction of 3D human facial images from DNA sequence, Advanced Science (2025).
Journal information: Advanced Science
Provided by Wiley
