麻豆淫院

Researchers at Kyushu University have developed a novel organic molecule that simultaneously exhibits two highly sought-after properties: efficient light emission suitable for advanced displays and strong light absorption for deep-tissue bioimaging. This breakthrough addresses a long-standing challenge in molecular design, paving the way for next-generation multifunctional materials.

Their study, published online in the journal on July 29, 2025, was conducted in collaboration with the National Taipei University of Technology and the National Central University.

Organic light-emitting diodes (OLEDs) are at the forefront of modern display and lighting technologies, powering nearly everything from smartphone screens to large televisions and monitors. A key phenomenon that is actively being researched to enhance OLED efficiency is thermally activated delayed fluorescence (TADF).

This process occurs when absorbed energy trapped in a non-light-emitting state (triplet state) is shifted into a light-emitting state (singlet state) using heat from the surroundings. In simple terms, materials exhibiting TADF can efficiently produce light from energy that would normally be lost, leading to brighter and more energy-efficient devices.

Beyond displays, the ability to capture sharp images of biological tissues while causing minimal harm is crucial for medical diagnostics and research. To this end, techniques leveraging two-photon absorption (2PA) have proven useful. In 2PA, instead of absorbing a single high-energy photon, a molecule absorbs two lower-energy photons simultaneously from a high-intensity laser to reach an excited state capable of emitting fluorescence.

Light with lower-energy photons and longer wavelengths, like near infrared, is ideal for biomedical imaging, since it can penetrate much deeper into tissues without scattering. As a bonus, 2PA means that only a small portion of tissue at the laser's focal point is excited, causing less damage to living cells.

Although TADF and 2PA are both desirable properties in organic materials鈥攐ne for efficient light emission, and the other for superior imaging鈥攃ombining both in a single molecule has been extremely challenging. This is because these mechanisms impose conflicting design requirements. Strong TADF calls for a twisted molecular structure that physically separates electron orbitals to facilitate energy conversion. In contrast, 2PA typically requires a more planar structure with significant orbital overlap to enable effective light absorption.

"Recognizing that these two functions have complementary advantages but conflicting molecular requirements, I was motivated to design a material that could harmonize both, ultimately aiming to create new multifunctional materials that could link the fields of electronics and life sciences," says Dr. Youhei Chitose, Assistant Professor of the Graduate School of Engineering at Kyushu University, Japan, and the lead author of the study.

To fill this knowledge gap, the research team employed a clever molecular design strategy. They created a molecule called CzTRZCN that acts as a molecular switch, changing its structure and properties depending on whether it's absorbing or emitting light. Their approach involved combining an electron-rich carbazole (Cz) compound with an electron-deficient triazine (TRZ) core. The researchers were able to fine-tune how the electrons grouped into orbitals within the structure by also adding cyano (CN) groups, which exert a strong pull onto electrons.

The end result meant that during light absorption, CzTRZCN maintains enough orbital overlap between its components to efficiently absorb two photons simultaneously. After excitation, the molecule undergoes structural changes that separate these components, enabling TADF.

Through a combination of theoretical calculations and experimental validation, the team demonstrated that their newly designed material achieved remarkable dual functionality. When integrated into an OLED device, CzTRZCN achieved an external quantum efficiency of 13.5%, establishing a new benchmark among triazine-based TADF materials. Moreover, it exhibited a high 2PA cross-section (a measure of 2PA efficiency) and high brightness, signifying its potential for medical imaging.

"The proposed molecule is a metal-free organic compound with low toxicity to cells and high biocompatibility. This makes it ideal for use in medical probes for precise cancer and neurological diagnostics, especially through time-resolved fluorescence microscopy," says Chitose.

Overall, this study represents an important step toward developing versatile organic materials that bridge the fields of photoelectronics and bioimaging. Beyond medical use, the proposed molecular design strategy for achieving different orbital characteristics for absorption and emission can be widely applied to other multifunctional materials.

"Moving forward, we aim to expand this molecular design approach to cover a broader range of emission wavelengths. We also plan to collaborate with researchers in biomedical and device engineering fields to explore the implementation of these materials in practical applications such as in vivo imaging, wearable sensors, and OLEDs," concludes Chitose.