/ en-us Â鶹ÒùÔº internet news portal provides the latest news on science including: Â鶹ÒùÔºics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Most people have encountered the black, gray, or pink stains of bacterial biofilms built up on the bathroom tiles or kitchen sink. Even with vigorous scrubbing and strong cleaning chemicals, this grime can be difficult to remove and often returns with vengeance. A new study, published in the Chemical Engineering Journal, reports a novel, two-step method to effectively dismantle bacterial biofilms and prevent regrowth. /news/2025-05-method-dismantles-bacterial-biofilms-regrowth.html Biochemistry Analytical Chemistry Thu, 22 May 2025 15:18:03 EDT news667145881 Sustainably produced, biodegradable materials are an important focus of modern materials science. However, when working with natural materials such as cellulose, lignin or chitin, researchers face a trade-off. Although these substances are biodegradable in their pure form, they are often not ideal when it comes to performance. Chemical processing steps can be used to make them stronger, more resistant or more supple—but in doing so, their sustainability is often compromised. /news/2025-05-versatile-fungi-based-material-resistant.html Biochemistry Materials Science Tue, 13 May 2025 11:09:03 EDT news666353341 A new study by Vanderbilt investigators has uncovered a previously unknown biological mechanism: how tissues detect and respond to damage in basement membranes, the thin layers of extracellular matrix that surround and support nearly every organ in the body. /news/2025-05-tissues-body-hidden.html Cell & Microbiology Molecular & Computational biology Mon, 12 May 2025 10:30:03 EDT news666264601 Cells have a mailing system of sorts. They can release tiny molecular balls, called extracellular vesicles (EVs), that contain biological matter or messages and attach to other cells to share whatever they contain. /news/2025-05-hood-probing-molecular-mechanisms-metastasis.html Bio & Medicine Mon, 05 May 2025 11:15:41 EDT news665662538 When children lose their baby teeth, there is an adult set already growing beneath the gums, ready to emerge. But if we lose our permanent teeth, there aren't any more waiting in the wings. Right now, the options for replacing these lost teeth are either dentures or titanium implants, neither of which provide the same function and feedback as a real, living tooth. /news/2025-04-pigs-regrow-adult-teeth-humans.html Cell & Microbiology Biotechnology Fri, 25 Apr 2025 17:05:20 EDT news664819509 The cells in human bodies are subject to both chemical and mechanical forces. But until recently, scientists have not understood much about how to manipulate the mechanical side of that equation. That's about to change. /news/2025-03-mechanical-encode-function-cells-fibrosis.html Cell & Microbiology Molecular & Computational biology Mon, 24 Mar 2025 14:16:04 EDT news662044561 A new study published in npj Science of Food reveals a breakthrough in cultured meat production, using Aloe vera as a natural, scalable, and cost-effective scaffold. This research was led by Dr. Gilad Gome, under the guidance of Dr. Sharon Schlesinger and Prof. Oded Shoseyov, from the Robert H. Smith Faculty of Agriculture, Food, and Environment at the Hebrew University of Jerusalem. /news/2025-03-cultured-meat-secret-ingredient-aloe.html Biotechnology Tue, 11 Mar 2025 10:04:03 EDT news660906241 Biofilms, ubiquitous bacterial communities embedded in a slimy matrix, are the oldest form of multicellularity on Earth; they are extremely resistant to antibiotics and stick tenaciously to most surfaces, including living tissue. /news/2025-03-sticky-situation-insights-antibiotic-resistant.html Ecology Cell & Microbiology Thu, 06 Mar 2025 12:11:03 EST news660485461 Cells have surface receptors called integrins that bind to repetitive domains present on the extracellular matrix (ECM) surrounding the cells, allowing them to grow and spread. A new study from the Department of Bioengineering (BE), Indian Institute of Science (IISc) and collaborators shows that tweaking the spacing between these binding domains on the ECM can boost the efficiency of ultrasound treatment applied to kill cancer cells. /news/2025-02-gold-nanodots-boost-cancer-cell.html Bio & Medicine Tue, 18 Feb 2025 03:20:01 EST news659067510 There are a multitude of products for sale that promise the appearance of eternal youth by erasing wrinkles or firming up jaw lines; but what if we could truly turn back time, at the cellular level? Now, researchers from Japan have found a protein that may do just that. /news/2025-02-key-protein-toggles-young-states.html Cell & Microbiology Molecular & Computational biology Mon, 17 Feb 2025 15:19:09 EST news659027946 Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came to the Pedram Lab to try something new. /news/2025-02-cells-microscopy-probe-unprecedented-view.html Cell & Microbiology Biotechnology Tue, 11 Feb 2025 15:19:04 EST news658509541 A research team from the Eye & ENT Hospital of Fudan University, China, has developed a novel biocompatible nanoadhesive for corneal transplantation. The nanoadhesive is based on tetrahedral framework nucleic acids combined with functionalized polycationic recombinant proteins. This unique composition minimizes the risks of tissue necrosis and inflammation associated with polymeric adhesives while inhibiting bacterial growth and promoting tissue repair. This work demonstrates an efficient strategy to break through the bottleneck of current ophthalmic adhesives. /news/2025-02-biocompatible-nanoadhesive-safer-corneal-transplants.html Bio & Medicine Mon, 10 Feb 2025 15:19:03 EST news658423141 Biological scientists from the National University of Singapore (NUS) have uncovered how the dengue virus uses its envelope protein to capture human plasmin from a blood meal to enhance the permeability of the mosquito midgut for infection. /news/2025-02-dengue-virus-infections-hijack-human.html Cell & Microbiology Molecular & Computational biology Mon, 03 Feb 2025 14:20:03 EST news657814801 Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed. Researchers at the Delft University of Technology in The Netherlands (TU Delft) have developed a 3D-printed brain-like environment where neurons grow similarly to a real brain. /news/2025-01-3d-nanopillars-mimic-brain-environment.html Bio & Medicine Nanomaterials Thu, 30 Jan 2025 04:00:01 EST news657302101 The fight against cancer often begins with uncovering hidden players, and a recent study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. /news/2025-01-decoding-link-lysosomal-focal-adhesions.html Cell & Microbiology Thu, 16 Jan 2025 04:22:53 EST news656223763 An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering. /news/2025-01-discovery-skeletal-tissue-advances-regenerative.html Cell & Microbiology Thu, 09 Jan 2025 16:35:04 EST news655662901 In mechanobiology, cells' forces have been considered fundamental to their enhanced function, including fast migration. But a group of researchers in the McKelvey School of Engineering at Washington University in St. Louis has found that cells can generate and use lower force yet move faster than cells generating and using high forces, turning the age-old assumption of force on its head. /news/2025-01-cell-migration-doesnt-generating.html Cell & Microbiology Molecular & Computational biology Thu, 09 Jan 2025 15:53:45 EST news655660413 Researchers from the Organoid group at the Hubrecht Institute have developed a new way to grow organoids. Organoids are tiny organs that are grown in the lab and mimic the original organ. The researchers were able to grow organoids using Invasin, a protein produced by bacteria. /news/2025-01-bacteria-sustainable-solution-organoids.html Cell & Microbiology Biotechnology Thu, 02 Jan 2025 11:20:01 EST news655037247 Your body is one of the most complex natural structures ever. Billions of cells are put together in a specific way with the result being you. If you look closely between the cells you'll find the extracellular matrix, a gel-like environment where cells reside and which helps them to talk to each other. However, when disease strikes, cells and the matrix alike can be irreparably damaged, which could lead to the loss of cell function. /news/2024-12-supramolecular-scaffolds-growth-human-cells.html Cell & Microbiology Biotechnology Tue, 24 Dec 2024 11:27:55 EST news654262070 When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breathe in and out. And tree-like blood vessels branch throughout our body, delivering oxygen from our head to our toes. /news/2024-12-molding-complex-tissues-gallium-method.html Cell & Microbiology Biotechnology Wed, 11 Dec 2024 11:08:07 EST news653137681 Developing reliable methods to replace dead or damaged tissue is one of the primary goals of regenerative medicine. With steady advances in tissue engineering and biomedicine, scientists are almost at a point where growing cell sheets in the lab and transplanting them onto damaged or diseased organs is becoming a reality rather than fiction. /news/2024-12-scientists-ultrasound-based-technique-tool.html Cell & Microbiology Biotechnology Thu, 05 Dec 2024 09:53:26 EST news652614800 An IBEC-led study has revealed how mesenchymal stem cells respond to the viscosity of their environment, a key aspect in their differentiation process. /news/2024-11-viscosity-materials-key-cell-differentiation.html Cell & Microbiology Biotechnology Mon, 18 Nov 2024 12:15:04 EST news651154501 To the casual eye, a memory foam mattress would appear to have no relationship to the behavior of cells and tissues. But an innovative study carried out at the Centro de Investigaciones Cardiovasculares (CNIC) in Madrid shows that viscoelasticity—the capacity of a material to be compressed and then recover its original form, like memory foam—is a little-explored property of biological tissues that is essential for correct cell function. /news/2024-11-uncovers-role-tissue-viscoelasticity-cell.html Cell & Microbiology Molecular & Computational biology Fri, 15 Nov 2024 14:00:01 EST news650893763 With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue. It is important to comprehensively and quantitatively evaluate the changes that aging causes at the molecular level in the body. By doing so, it may be possible to pinpoint specific aging factors and suppress age-related diseases. /news/2024-11-age-molecular-quantitative-wide-range.html Cell & Microbiology Molecular & Computational biology Fri, 15 Nov 2024 11:49:58 EST news650893796 Antibiotics have saved millions of lives from infectious diseases and are considered one of the most important discoveries of the 20th century. However, as the use (and abuse) of antibiotics has increased over the years, many bacteria have developed resistance to these drugs. /news/2024-11-human-histones-bacterial-infections.html Cell & Microbiology Molecular & Computational biology Fri, 01 Nov 2024 10:33:04 EDT news649675981 A research team led by Prof. Hans-Curt Flemming from the Institute of Oceanology of the Chinese Academy of Sciences (IOCAS) has reported on the role of extracellular polymeric substances of biofilms in a study published in Nature Reviews Microbiology on Sep. 27. /news/2024-10-scientists-explore-role-extracellular-polymeric.html Cell & Microbiology Molecular & Computational biology Thu, 31 Oct 2024 11:14:45 EDT news649592082 Genes are the control panel for an embryo morphing from a ball of cells into organs, muscles, and limbs, but there's more involved than just genetics. There's also physics—the shaping of tissues by flows and forces from cellular activity and growth. /news/2024-10-gut-genetics-physics-embryonic.html Cell & Microbiology Molecular & Computational biology Wed, 16 Oct 2024 14:44:10 EDT news648308636 The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations. Optical phenotypes are typically inaccessible for sequencing-based approaches based on cell lysis but include crucial information such as cell morphology, protein subcellular localization, cell-cell interactions, extracellular matrix factors, and tissue organization. /news/2024-10-scientists-method-gene-function-cells.html Biotechnology Molecular & Computational biology Mon, 14 Oct 2024 08:25:57 EDT news648113152 Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events. Now, new research from the Stowers Institute for Medical Research has unveiled a critical timing factor—specifically how long cells actively respond to injury—involved in regulating regeneration. /news/2024-09-scientists-uncover-critical-component-killifish.html Plants & Animals Molecular & Computational biology Thu, 26 Sep 2024 12:35:40 EDT news646572928 A research team consisting of Professor Dong Sung Kim, Professor Anna Lee, and Dr. Jaeseung Youn from the Department of Mechanical Engineering at POSTECH has successfully recreated the structure of wrinkles in biological tissue in vitro, uncovering the mechanisms behind their formation. Their findings were published on August 19 in the journal Nature Communications. /news/2024-09-mystery-human-wrinkles-cells.html Cell & Microbiology Molecular & Computational biology Thu, 19 Sep 2024 12:00:08 EDT news645966001