/ en-us Â鶹ŇůÔş internet news portal provides the latest news on science including: Â鶹ŇůÔşics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. In the past, scientists believed that the fast-acting biochemistry of genes and proteins was responsible for directing the forces that shape developing organs. But a new study from Syracuse University shows that steady, powerful flows of tissue might be equally significant in shaping an organ's development as biochemistry. By understanding this physical process, doctors could find ways to prevent or treat human illness. /news/2025-08-steady-tissue-important-genes-biochemistry.html Molecular & Computational biology Thu, 21 Aug 2025 14:56:03 EDT news675006961 More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those in need but, importantly, also for new biomedical solutions that can address the root causes of infertility. /news/2025-08-lab-grown-stem-cells-key.html Biotechnology Molecular & Computational biology Sun, 17 Aug 2025 06:24:48 EDT news674630549 A research team has developed a nanobody-based technology that can precisely identify and attack only lung cancer cells, opening new possibilities for cancer therapy. /news/2025-08-precision-nanobody-drone-lung-cancer.html Bio & Medicine Fri, 15 Aug 2025 09:49:04 EDT news674470142 Research from an international team finds that the human gut is a site of rapid change, with recent and important deviations from other mammals, including our closest living relative, the chimpanzee. /news/2025-08-human-intestine-rapid-evolutionary-mammals.html Evolution Cell & Microbiology Wed, 06 Aug 2025 14:41:02 EDT news673710058 A research team led by Professor Takuya Yamamoto and Assistant Professor Ryusaku Matsumoto (Department of Life Science Frontiers) has developed a machine learning model that enables early prediction of hypothalamus–pituitary organoid formation from human iPS cells to aid in organoid research and regenerative medicine. /news/2025-08-stem-cell-derived-organoid-quality.html Cell & Microbiology Biotechnology Tue, 05 Aug 2025 10:01:03 EDT news673606861 Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their structures. The research group of the Molecular Microscopy and Spectroscopy Lab at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) in Genoa has devised a new method that allows scientists to see and photograph biological samples in all their complexity, obtaining clear and detailed images. The new technique has been made available to the scientific community in "open science" mode, representing an advantage in the biomedical field, since it allows us to observe active cells, even in the presence of diseases, as well as to understand how drugs interact with living tissues. /news/2025-07-microscopy-method-reveals-images-complex.html Optics & Photonics Thu, 24 Jul 2025 12:40:03 EDT news672578634 Bioengineered organs are no longer just structural substitutes. A review published in Trends in Biotechnology introduces a groundbreaking concept: biohybrid-engineered tissue (BHET) platforms—living constructs integrated with electronics that can monitor, modulate, and even autonomously control their own functions. /news/2025-07-passive-intelligent-bioengineered-electronics.html Biotechnology Fri, 18 Jul 2025 09:33:06 EDT news672049982 Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, provides a potentially higher barrier to resistance than conventional therapies and could be beneficial in the treatment of diseases, particularly in the case of emerging viruses. /news/2025-07-emerging-viral-threats-combated-potent.html Molecular & Computational biology Mon, 14 Jul 2025 09:30:01 EDT news671703072 The time it takes to grow new skin for burns victims could be improved thanks to a new method of cell cultivation using algae, developed by University of Queensland researchers. /news/2025-07-algae-cheaper-greener-ethical-cells.html Cell & Microbiology Biotechnology Thu, 10 Jul 2025 10:08:03 EDT news671360881 Northwestern Medicine scientists have discovered a previously unknown process used by epithelial cells to alleviate epithelial tissue crowding and avoid cell damage and loss, according to a recent study published in Nature Communications. /news/2025-06-epithelial-cells-reveal-mechanism-ease.html Cell & Microbiology Molecular & Computational biology Tue, 24 Jun 2025 14:32:03 EDT news669994321 In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The results, published in the open-access journal PLOS Biology, offer new hope for people with rare genetic conditions. /news/2025-06-scientists-gene-mitochondrial-mutations-human.html Cell & Microbiology Biotechnology Tue, 24 Jun 2025 14:00:01 EDT news669972362 Nanoplastics can compromise intestinal integrity in mice by altering the interactions between the gut microbiome and the host, according to a paper in Nature Communications. The study explores the complex interactions of nanoplastics with the gut microenvironment in mice. /news/2025-06-nanoplastics-disrupt-gut-microbes-mice.html Bio & Medicine Tue, 10 Jun 2025 14:49:05 EDT news668785741 Researchers at Helmholtz Munich and the Technical University of Munich have developed a new microscope that significantly improves how bioluminescent signals in living cells can be observed. /news/2025-05-quanta-image-sensors-bioluminescent-sharper.html Optics & Photonics Thu, 29 May 2025 12:08:55 EDT news667739330 Living in a murky lake around Mexico City, surrounded by aggressive and cannibalistic neighbors, the axolotl lives at constant risk of losing a limb to a neighbor's nibble. Fortunately, lost limbs regrow and are functional in as few as eight weeks. To achieve this feat, the regrowing body parts must "know" their position within the axolotl body to regenerate the right structure for a specific location. /news/2025-05-hand2-positional-code-axolotls-regrow.html Biotechnology Molecular & Computational biology Wed, 21 May 2025 11:00:06 EDT news667043180 Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular "traffic cops" known as morphogens regulate the activation of gene programs that initiate stem cells' differentiation into more specialized brain cells. /news/2025-05-morphogens-early-brain-stem-cell.html Cell & Microbiology Molecular & Computational biology Thu, 01 May 2025 14:11:04 EDT news665327461 The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation—the process by which stem cells give rise to specialized cells that make up all the body's tissues. /news/2025-03-glucose-life-reveals-role-master.html Cell & Microbiology Molecular & Computational biology Wed, 26 Mar 2025 12:02:00 EDT news662209316 The journal Advanced Materials recently published a study introducing a new method for monitoring molecular processes deep within tissue. Developed at the Technion–Israel Institute of Technology, the innovation is expected to accelerate key advancements in personalized medicine, cancer diagnosis, and early disease detection. /news/2025-03-insect-vision-noninvasive-method-deep.html Biotechnology Molecular & Computational biology Fri, 07 Mar 2025 04:29:36 EST news660544173 Metabolic imaging is a noninvasive method that enables clinicians and scientists to study living cells using laser light, which can help them assess disease progression and treatment responses. /news/2024-12-noninvasive-imaging-method-penetrate-deeper.html Cell & Microbiology Biotechnology Wed, 11 Dec 2024 14:00:01 EST news653131806 When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are interpreted by developing cells remains unclear. A team of researchers at the Institute of Science and Technology Austria (ISTA) now has more insights—thanks to miniature 2D organs and rubbery silicone molds. /news/2024-11-tissue-temporally.html Cell & Microbiology Molecular & Computational biology Wed, 27 Nov 2024 12:30:04 EST news651933001 Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a neotype lysosomal trap for clearing viruses and variants. This lysosomal "TRAP" (lysoTRAP) shows efficient viruses and variants infection inhibition potential in cell, mouse, hamster, and human lung organoid models. /news/2024-11-lysosomal-clearance-viruses-variants.html Biotechnology Molecular & Computational biology Tue, 26 Nov 2024 11:02:16 EST news651841329 A team of neurologists, bioengineers and radiologists has found that two neurons in the human brain that code for dopamine production have to work harder than similar cells in primate relatives. The group has posted a paper describing their work on the bioRxiv preprint server. /news/2024-11-human-brain-organelles-dopamine-neurons.html Evolution Cell & Microbiology Mon, 18 Nov 2024 11:30:01 EST news651148682 Bioprinting is a technology used to create three-dimensional structures, such as human tissues or organs, using bio-inks made of cells and hydrogels. However, conventional inkjet technology has difficulty dispensing bio-inks that are sensitive to temperature due to the heat generated during operation. /news/2024-11-high-inkjet-bioprinting-productivity.html Materials Science Tue, 12 Nov 2024 14:00:08 EST news650642401 Recent advances that have enabled the growth of tissue cultures into organoids and embryoids have heightened interest as to how tissue growth is controlled during the natural processes of embryo development. It is known that the diffusion of signaling molecules called morphogens directs patterned tissue growth, but what has been harder to understand is how the gradient of morphogens from this diffusion can lead to sharply defined domains in the resulting tissue. /news/2024-10-collaboration-tissues-sharply.html Cell & Microbiology Biotechnology Tue, 08 Oct 2024 10:55:04 EDT news647603702 Measuring and analyzing three-dimensional (3D) images of live cells and tissues is considered crucial in advanced fields of biology and medicine. Organoids, which are 3D structures that mimic organs, are particular examples that significantly benefit 3D live imaging. Organoids provide effective alternatives to animal testing in the drug development processes, and can rapidly determine personalized medicine. On the other hand, active research is ongoing to utilize organoids for organ replacement. /news/2024-08-paper-strategies-holotomography-advanced-bio.html Cell & Microbiology Molecular & Computational biology Tue, 27 Aug 2024 11:52:37 EDT news643978352 Researchers are expanding the possibilities of 3D printing to create miniature human organs and a variety of products made from living tissue, including food. /news/2024-08-3d-cells-pave-tomorrow-medicine.html Cell & Microbiology Biotechnology Mon, 26 Aug 2024 09:29:05 EDT news643883341 An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. The team's findings, published in Developmental Cell, could lead to new ways to fight a host of skin diseases, including ulcers and skin cancer. /news/2024-08-proteins-skin-strength-cell.html Cell & Microbiology Molecular & Computational biology Wed, 21 Aug 2024 10:22:03 EDT news643454521 An international team of neurobiologists has developed a way to use a parasite to deliver protein therapies through the blood–brain barrier to treat nerve cell disorders. In their study published in Nature Microbiology, the group engineered the parasite Toxoplasma gondii to produce a protein to treat a brain disorder. /news/2024-07-parasite-therapy-proteins-nerve-cells.html Cell & Microbiology Biotechnology Tue, 30 Jul 2024 08:27:00 EDT news641546812 In a paper published in hLife, a team of Chinese scientists describes simple procedures for generating mouse and bovine cholangiocyte organoids (Chol-orgs) and establishing an in vitro system for culturing Cryptosporidium and transcriptomic studies of biliary cryptosporidiosis. /news/2024-07-team-simple-generate-mouse-bovine.html Biotechnology Molecular & Computational biology Mon, 08 Jul 2024 15:58:34 EDT news639673112 In sciences, disruptive research that is breaking new ground often raises new and not-yet-explored ethical questions. Although new scientific breakthroughs can have the power to change how we understand and live in the world, the ethical implications of technologies that will emerge based on these new insights can affect an emerging field's public acceptance and have moral implications for society at large. They can also impact the process of translating discoveries into real-world products, sometimes requiring new regulations. /news/2024-06-collaborative-ethics-fundamental-discoveries-real.html Other Tue, 25 Jun 2024 12:20:06 EDT news638536794 How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs' line of defense. /news/2024-06-lung-organoids-reveal-pathogens-infect.html Cell & Microbiology Molecular & Computational biology Mon, 10 Jun 2024 09:50:24 EDT news637231821