/ en-us Â鶹ÒùÔº internet news portal provides the latest news on science including: Â鶹ÒùÔºics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. In the past, scientists believed that the fast-acting biochemistry of genes and proteins was responsible for directing the forces that shape developing organs. But a new study from Syracuse University shows that steady, powerful flows of tissue might be equally significant in shaping an organ's development as biochemistry. By understanding this physical process, doctors could find ways to prevent or treat human illness. /news/2025-08-steady-tissue-important-genes-biochemistry.html Molecular & Computational biology Thu, 21 Aug 2025 14:56:03 EDT news675006961 Cell culture is a foundational technology widely used across fields such as pharmaceutical production, regenerative medicine, food science, and materials engineering. A critical component of successful cell culture is the culture medium—a solution containing essential nutrients that support cell growth. /news/2025-08-ai-biological-variability-high-serum.html Biotechnology Molecular & Computational biology Tue, 19 Aug 2025 15:51:03 EDT news674837461 One of the most significant moments in the evolutionary journey of life on this planet was the transition from water to land. This huge step required animals to adapt to new challenges, including supporting their body weight and developing new modes of locomotion. These changes put increased pressure on weight-bearing skin, such as paws and soles. /news/2025-08-gene-linked-skin-resistance-pressure.html Evolution Molecular & Computational biology Tue, 12 Aug 2025 14:30:02 EDT news674226111 Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies. /news/2025-08-nascent-rna-profiling-uncovers-molecular.html Cell & Microbiology Molecular & Computational biology Fri, 08 Aug 2025 09:44:04 EDT news673865041 Researchers at UBC Okanagan have made two major discoveries that are set to revolutionize how scientists observe and measure molecular forces within living cells. /news/2025-08-molecular-imaging-tech-cells-nanometer.html Biotechnology Molecular & Computational biology Thu, 07 Aug 2025 11:46:04 EDT news673785961 A research team led by Professor Takuya Yamamoto and Assistant Professor Ryusaku Matsumoto (Department of Life Science Frontiers) has developed a machine learning model that enables early prediction of hypothalamus–pituitary organoid formation from human iPS cells to aid in organoid research and regenerative medicine. /news/2025-08-stem-cell-derived-organoid-quality.html Cell & Microbiology Biotechnology Tue, 05 Aug 2025 10:01:03 EDT news673606861 Microrobots formed in droplets could enable precision-targeted drug delivery, improving on I.V. drug delivery that sends only 0.7% of the drug to the target tissue, according to a recent study in Science Advances, conducted through simulations at the University of Michigan and experiments at the University of Oxford. /news/2025-07-microrobots-drugs-drug-delivery.html Bio & Medicine Nanomaterials Thu, 31 Jul 2025 15:57:13 EDT news673196227 A team of researchers has recently developed a nondestructive imaging and machine learning system that accurately predicts the efficiency of stem cell differentiation into muscle stem cells. The team was led by Associate Professor Hidetoshi Sakurai (Department of Clinical Application) in collaboration with Epistra Inc. The work is published in Scientific Reports. /news/2025-07-ai-muscle-stem-cell-yield.html Cell & Microbiology Biotechnology Thu, 24 Jul 2025 08:40:01 EDT news672565041 Researchers from Japan and France have successfully reconstituted the development of mouse egg cells, known as oocytes, from embryonic stem cells entirely in vitro, without the need for ovarian support cells. This new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for future applications in human reproductive biology. The findings are published in the journal Developmental Cell. /news/2025-07-scientists-recreate-mouse-egg-cell.html Cell & Microbiology Molecular & Computational biology Tue, 22 Jul 2025 11:10:21 EDT news672401126 In a breakthrough for regenerative medicine, a new study from IMDEA Materials Institute researchers has demonstrated the potential of 3D-printed carbon microlattices as structurally tunable scaffolds for bone tissue engineering. /news/2025-07-3d-carbon-scaffolds-potential-bone.html Bio & Medicine Nanomaterials Tue, 22 Jul 2025 11:00:09 EDT news672399718 Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging. /news/2025-07-cells-toxic-dna-linked-cancer.html Cell & Microbiology Molecular & Computational biology Mon, 21 Jul 2025 10:02:05 EDT news672310915 A host of scientific investigations await the crew of NASA's SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity's effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients. /news/2025-07-nasa-spacex-crew-mission-gears.html Space Exploration Wed, 16 Jul 2025 11:00:14 EDT news671881142 Scientists have created a more efficient and controlled way to produce lab-grown inner ear hair cells than current methods allow, offering a new tool for hearing loss research. /news/2025-07-approach-generating-ear-hair-cells.html Cell & Microbiology Molecular & Computational biology Tue, 15 Jul 2025 14:49:17 EDT news671809752 While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ears are damaged, the result is often permanent hearing loss, deafness, or balance problems. In contrast, animals like fish, frogs, and chicks regenerate sensory hair cells effortlessly. /news/2025-07-regrowing-cells-gene-functions-zebrafish.html Cell & Microbiology Molecular & Computational biology Mon, 14 Jul 2025 05:00:04 EDT news671448440 For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained classic Mendelian traits, such as how single DNA mutations in protein-coding regions could cause diseases like sickle cell anemia. Yet, this accounts for only about 2% of Mendelian inheritance and the resulting phenotypic changes. /news/2025-07-rna-revolution-life-blueprint-rewritten.html Molecular & Computational biology Thu, 10 Jul 2025 12:00:01 EDT news671364617 The time it takes to grow new skin for burns victims could be improved thanks to a new method of cell cultivation using algae, developed by University of Queensland researchers. /news/2025-07-algae-cheaper-greener-ethical-cells.html Cell & Microbiology Biotechnology Thu, 10 Jul 2025 10:08:03 EDT news671360881 Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune system. The new approach, described in the journal Materials Today Bio, could improve stem cell-based treatments for conditions such as heart disease, liver damage, and autoimmune illnesses. /news/2025-07-aligned-stem-cell-sheets-boost.html Cell & Microbiology Biotechnology Thu, 03 Jul 2025 15:43:03 EDT news670776181 Cell sheet preparation for use in tissue engineering and regenerative therapies could be significantly improved with the use of thermo-responsive polymer brushes, adjusted in length and density according to specific cell types. /news/2025-07-cell-sheet-production-efficiency-greatly.html Cell & Microbiology Biotechnology Thu, 03 Jul 2025 13:23:04 EDT news670767782 Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology. The AT2-like cells were generated in just 7 to 10 days—a significant reduction compared to the approximately one month typically required by conventional stem cell-based differentiation methods. /news/2025-07-lung-cells-generated-mouse-fibroblasts.html Cell & Microbiology Biotechnology Thu, 03 Jul 2025 12:28:03 EDT news670764481 Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a team effort to develop a novel RNA-based system called the split RNA switch, integrating translational and post-translational control to achieve highly specific gene expression in targeted cell types. Their study is published in Nature Communications. /news/2025-07-rna-boosts-precision-cell-specific.html Biotechnology Molecular & Computational biology Thu, 03 Jul 2025 11:47:42 EDT news670762053 Research led by the National Institute of Biological Sciences in Beijing has discovered that switching on a single dormant gene enables mice to regenerate ear tissue. /news/2025-06-silent-gene-revives-tissue-regeneration.html Biotechnology Molecular & Computational biology Mon, 30 Jun 2025 11:50:07 EDT news670502862 Mesenchymal stem cells (MSCs), which can be harvested from fat and bone marrow, have immune-modulating and anti-inflammatory effects that are beneficial for both human and veterinary medicine. However, MSCs have a limited proliferation capacity, with their quality varying depending on the donor's age and where they were harvested from. /news/2025-06-canine-medicine-high-quality-stem.html Biotechnology Veterinary medicine Fri, 20 Jun 2025 10:49:51 EDT news669635387 Tiny gel droplets enhanced with University of Queensland technology could open new pathways to repairing and replacing damaged organs. /news/2025-06-microfluidic-technology-pathways.html Biotechnology Molecular & Computational biology Thu, 19 Jun 2025 07:19:04 EDT news669536342 Modern humans have existed for more than 200,000 years, and each new generation has begun with a single cell—dividing, changing shape and function, organizing into tissues, organs, and limbs. With slight variations, the process has repeated billions of times with remarkable fidelity to the same body plan. /news/2025-06-cells-anthrobots-biologically-younger.html Cell & Microbiology Biotechnology Wed, 18 Jun 2025 10:20:01 EDT news669460515 Northwestern Medicine scientists have discovered how cells responsible for hair growth perceive physical forces in their environment and utilize that information to regulate their growth, according to a study published in Science Advances. /news/2025-06-hair-follicles-environment.html Cell & Microbiology Molecular & Computational biology Tue, 17 Jun 2025 13:06:57 EDT news669384405 Axolotls are known for their ability to regrow limbs, organs and even parts of the brain and heart. But the tailed amphibian with the scientific name Ambystoma mexicanum can do even more. Its mucous membrane protects it from pathogens, more precisely: the antimicrobial peptides (AMP) it contains. This property makes the amphibian interesting in medicine, as the increasing resistance of bacteria to antibiotics is a major problem in the health care sector. /news/2025-06-axolotl-skin-mucus-potential-weapon.html Cell & Microbiology Biotechnology Tue, 17 Jun 2025 09:52:05 EDT news669372722 Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond. /news/2025-06-advanced-software-uncovers-elusive-protein.html Biotechnology Molecular & Computational biology Mon, 16 Jun 2025 13:57:11 EDT news669301020 In most vertebrates, skin appendages such as hair, feathers, or scales originate from placodes—small, specialized skin regions whose spatial organization is controlled by well-conserved genetic signals. Crocodiles are an exception: their head scales do not emerge from placodes but result from simple mechanical folding of the growing skin. /news/2025-06-patterns-sculpted-physics-evolution-revealed.html Evolution Molecular & Computational biology Tue, 10 Jun 2025 12:18:04 EDT news668776682 The stem cell-based embryo model (SCBEM) takes advantage of the flexibility of pluripotent stem cells (non-reproductive cells that can give rise to many different types of cells) to resemble that of embryos. While this model has helped to advance research in diseases and develop therapies or treatments, it has also sparked international debate on what regulations should be placed on this type of experimentation. /news/2025-06-stem-cell-based-embryo-important.html Cell & Microbiology Biotechnology Tue, 10 Jun 2025 11:32:51 EDT news668773962 Axolotls, with their signature smiles and pink gills, are the celebrities of the salamander world. But they are more than just cute: They might also hold the secret to regenerating human limbs. /news/2025-06-axolotls-regenerate-limbs-uncover-secret.html Plants & Animals Molecular & Computational biology Tue, 10 Jun 2025 10:57:03 EDT news668771821