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Cell & Microbiology Jun 24, 2025

Scientists use gene editing to correct harmful mitochondrial mutations in human cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The results, published in the open-access ...

Evolution Jun 24, 2025

Tomatoes in the Galápagos are quietly de-evolving

On the younger, black-rock islands of the Galápagos archipelago, wild-growing tomatoes are doing something peculiar. They're shedding millions of years of evolution, reverting to a more primitive genetic state that resurrects ...

Cell & Microbiology Jun 24, 2025

Barcodes uncover early blueprints of our cellular origins

A study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies.

Biochemistry Jun 23, 2025

Biosensor-guided evolution enhances itaconic acid production in E. coli

A novel evolutionary technique, designed to select E. coli strains capable of more efficiently metabolizing acetate—a sustainable, cost-effective carbon source—has been developed by a research team led by Professor Donghyuk ...

Biochemistry Jun 23, 2025

Upcycling plastic into painkillers: Microbes transform everyday waste into acetaminophen

Paracetamol (acetaminophen) production could be revolutionized by the discovery that a common bacterium can turn everyday plastic waste into the painkiller. The new method leaves virtually no carbon emissions and is more ...

Cell & Microbiology Jun 23, 2025

Scalable toolkit streamlines genetic engineering of yeast for industrial biotechnology

Researchers at DTU Biosustain (The Novo Nordisk Foundation Center for Biosustainability at DTU) have developed a new tool that significantly accelerates and simplifies the genetic engineering of yeast strains used in industrial ...

Bio & Medicine Jun 23, 2025

Lipid nanoparticles that engineer CAR T cells in vivo could unlock access for millions of autoimmune patients

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted lipid nanoparticles (tLNPs) ...

Cell & Microbiology Jun 23, 2025

Synthetic 'killswitch' uncovers hidden world of cellular condensates

Researchers at the Max Planck Institute for Molecular Genetics have developed a novel synthetic micropeptide termed the "killswitch" to selectively immobilize proteins within cellular condensates, unveiling crucial connections ...

Cell & Microbiology Jun 23, 2025

Study reveals how wheat roots are quietly engineering their microbiomes

In an advance for agriculture, a new study reveals how wheat plants actively influence the microbial communities living on and inside their roots—and how these root microbiomes change over time depending on conditions such ...

Biochemistry Jun 23, 2025

Engineers turn toxic ancient tomb fungus into anti-cancer drug

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient ...

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