Enantioselectivity plays an important role in the pharmacological and toxicological processes of chiral drugs.
The concept of chirality is well-established in science: when an object cannot be superimposed on its mirror image, both the object and its mirror image are called chiral. In the drug industry, for instance, more than 50% ...
Researchers of Tomsk Polytechnic University with colleagues from the Czech Republic have developed supersensitive sensors for detecting enantiomers, known as "mirror molecules," in drugs. These molecules can reduce drug effectiveness ...
Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.
Researchers here have come up with a strategy to make a transition metal-catalysed chemical reaction enantioselective through the use of a chiral cation. The work was carried out in Dr. Robert Phipps's research group.
Efforts to develop heterogeneous catalysts that appeal to the fine chemical industry have been limited by underwhelming results. Although some approaches have shown promising catalytic activity, "heterogenization" itself ...
Researchers from Osaka University optimize a complicated domino reaction in a flow system via machine learning to efficiently screen multiple variables, attaining high selectivity and yield of a potential biologically active ...
A team of researchers at California Institute of Technology has found a nickel catalyst that bonds alkyl nucleophile and alkyl electrophiles to make a single stereoisomer with two chiral centers. In their paper published ...
The Nitschke Group at the University of Cambridge designs hollow molecules that act as capsules or cages that enclose guest molecules. These cages have exciting potential applications in a variety of fields. They could, for ...
Many of the molecular building blocks of life have two versions that are mirror images of one another, known as enantiomers. Although seemingly identical, the two enantiomers can have completely different chemical behaviour—a ...
