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Search results for CRISPR-Cas9

Cell & Microbiology Jul 8, 2024

Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci

DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative ...

Molecular & Computational biology Jul 5, 2024

Tomato timekeeper: SlNF-YA3b gene's role in flowering time revealed

Controlling the timing of flowering in crops is crucial for optimizing yields and adapting to climate changes. Researchers have identified a specific gene in tomatoes that regulates this critical phase, providing a significant ...

Molecular & Computational biology Jul 5, 2024

Scientists uncover conserved mechanism of pericentric heterochromatin initiation in vertebrates

A study published in Nature on July 4 by Prof. Zhu Bing from the Institute of Biophysics of the Chinese Academy of Sciences has shed light on the conserved mechanism responsible for the initiation of pericentric heterochromatin ...

Agriculture Jun 28, 2024

Mutations in wheat TaAPA2 gene result in pleiotropic effects on plant architecture

This study is reported by Shisheng Chen's group at the National Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences. Plant architecture has significant impact on plant development ...

Molecular & Computational biology Jun 27, 2024

A new CRISPR-driven technology for gene drive in plants

Weeds are a pesky irritant for most home gardeners, but in large agricultural settings, weeds can pose an especially deadly problem. For example, Amaranthus palmeri, known as Palmer's pigweed, has evolved in many areas to ...

Molecular & Computational biology Jun 25, 2024

Researchers discover MAPK20-ATG6 link in tomato pollen vitality

Pollen development in flowering plants is a complex process involving multiple genetic and physiological pathways. Previous studies have highlighted the importance of mitogen-activated protein kinases (MAPKs) in various plant ...

Cell & Microbiology Jun 21, 2024

Inspired by nature: Synthetic nightshade molecule effective against leukemia cells

Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia ...

Ecology Jun 18, 2024

Odors are encoded in rings in the brains of migratory locusts, finds study

In a study published in the journal Cell, a team of researchers from the Max Planck Institute for Chemical Ecology in Jena, Germany, describes for the first time how odors are encoded in the antennal lobe, the olfactory center ...

Plants & Animals Jun 17, 2024

Overriding Mendel's laws: Researchers develop plant gene drive system for enhanced trait inheritance

A collaborative research team has developed a plant gene drive system called CRISPR-Assisted Inheritance utilizing NPG1 (CAIN), which, according to the researchers, uses a toxin-antidote mechanism in the male germline to ...

Biotechnology Jun 15, 2024

Some CRISPR screens may be missing cancer drug targets

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and ...

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