When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation. A new chemical tool developed at UC Riverside interrupts that process, helping ...
Researchers from Cornell and Northwestern universities have developed a rapid, cell-free method for building nanoparticle vaccines that mimic viruses at the molecular level, offering a powerful new tool for responding to ...
Since the Human Genome Project first produced the genetic instructions for a human being by sequencing DNA 22 years ago, scientists have been focused on roughly 2% of the genome-producing proteins.
Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in unspooling DNA so that it can undergo repair. Because this protein is critical for DNA repair for ...
Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, provides ...
Weizmann Institute of Science-led researchers have unveiled a computational workflow that crafts enzymes exhibiting catalytic efficiencies surpassing 100,000 M−1 s−1, achieving performance comparable to natural biocatalysts ...
Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By linking a disease-related protein to one that triggers a cell's demolition and recycling pathways, ...
Using a high-throughput fluorescence microscopy system and machine learning algorithms, oxidative stress-related changes in protein localization have been mapped by researchers from Japan. Furthermore, a comprehensive database ...
In a significant step toward improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier system that delivers therapeutic antibodies directly to target antigens inside cancer cells.
Researchers have developed a wireless implantable drug delivery system that enables anticancer drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue. The multidisciplinary team, led by experts ...
