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Search results for CRISPR-Cas9

Molecular & Computational biology May 25, 2024

New study discovers tiny target on RNA to short-circuit inflammation

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening process based on the powerful ...

Plants & Animals May 22, 2024

Research improves multiplex mutagenesis to increase experimental efficiency in plant genome editing

CRISPR/Cas9 remains the most powerful tool to generate mutations in plant genomes. Studying the various combinations of mutations has significantly increased the scale of experimental setups, necessitating more space to grow ...

Biotechnology May 20, 2024

A new chapter in grape cultivation: Non-transgenic plant regeneration technology

Traditional genome editing techniques encounter significant challenges in vegetatively propagated crops like grapes. Current transformation methods exhibit low efficiency and face difficulties in achieving stable plant regeneration ...

Plants & Animals May 20, 2024

Exploring the multifaceted role of MicroRNA156 in horticultural plants

A research team has reviewed the role of MicroRNA156 (miR156) in horticultural plants, uncovering its significant influence on a variety of biological processes such as vegetative growth, floral induction, and stress response. ...

Biotechnology May 17, 2024

Researchers use machine-learning modeling tools to improve zinc-finger nuclease editing technology

Genome editing is making inroads into biomedical research and medicine. By employing biomolecule modeling tools, a Japanese research team is accelerating the pace and cutting the cost of zinc finger nuclease (ZFN) technology, ...

Biotechnology May 15, 2024

New strategy suppresses unwanted deletion events to make genome editing safer and more precise

A simple and robust strategy developed by KAUST scientists could help to improve the safety and accuracy of CRISPR gene editing, a tool that is already approved for clinical use for the treatment of inherited blood disorders.

Cell & Microbiology May 7, 2024

Researchers study the intricacies of homologous recombination and abnormal chromosome bridges

Keeping the genetic information stored in genomic DNA intact during the cell division cycle is crucial for almost all lifeforms. Extensive DNA damage invariably causes various adverse genomic rearrangements, which can lead ...

Cell & Microbiology May 7, 2024

Microbiome studies help explore treatments for genetic disorders

A collaboration has led to the identification, in a bacterium of the intestine, of new CRISPR-Cas9 molecules that could have a clinical potential to treat genetic diseases such as retinitis pigmentosa, through sub-retinal ...

Biotechnology Apr 29, 2024

Scientists' research on RNA editing illuminates possible lifesaving treatments for genetic diseases

A team at Montana State University published research this month that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating ...

Plants & Animals Apr 29, 2024

Aggressive wall lizard provides clues to understanding evolution

Body shape, color and behavior often evolve together as species adapt to their environment. Researchers from Lund University in Sweden have studied this phenomenon in a specific type of large, bright green and aggressive ...

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