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Search results for therapeutic protein

Molecular & Computational biology May 23, 2025

Microscopic movies capture brain proteins in action, revealing new insight into shapes and functions

Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways (called microtubules) ...

Cell & Microbiology May 23, 2025

Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are bound for secretion harbor ...

Biochemistry May 22, 2025

One-pot protein screening accelerates bioscience and drug discovery

Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic candidates, like antibodies that bind to and fight the SARS-CoV-2 virus, can be explored and simulated ...

Bio & Medicine May 21, 2025

Engineered bacteria can deliver antiviral therapies and vaccines

New research from the University of Cincinnati demonstrates how specially engineered bacteria taken orally can operate as a delivery system for antiviral therapies and vaccines. The research, led by Nalinikanth Kotagiri, ...

Cell & Microbiology May 21, 2025

Mapping ATP's journey: Key protein identified as gateway for energy delivery into endoplasmic reticulum

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect ...

Bio & Medicine May 18, 2025

Nanoparticle-cell interface enables electromagnetic wireless programming of mammalian transgene expression

Recent technological advances are fueling the development of cutting-edge technologies that can monitor and control physiological processes with high precision. These include devices that could control the expression of genes ...

Biotechnology May 15, 2025

Cas9 ancestor engineered into a compact genome editing tool

Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. The engineered protein, ...

Biotechnology May 14, 2025

Q&A: A generative AI technique for designing RNA with improved function

Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a plethora of functions, ...

Cell & Microbiology May 13, 2025

AI can identify genetic perturbations from cell images, offering new path for drug discovery

Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to identifying genetic perturbation patterns in cell images—potentially enabling the development of new ...

Biotechnology May 12, 2025

Q&A: AI speeds up search for RNA-targeting drugs, opening new therapeutic possibilities

The majority of RNAs in each of our cells don't code for any of the thousands of proteins that make up our bodies. Instead, noncoding RNAs have critical roles in many biological processes—such as gene expression—making ...

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