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Bio & Medicine Feb 18, 2025

Self-protecting nanoparticles can enhance colorectal cancer drug delivery

Colorectal cancer (CRC) is one of the most prevalent types of cancer and has a high mortality rate globally. Oral administration of anticancer drugs that pass through the gastrointestinal (GI) tract into the colorectum is ...

Bio & Medicine Feb 18, 2025

New gold nanoparticle-based therapy shows promise in colorectal cancer treatment

Luminescent gold nanoparticles (L-AuNPs) represent a novel class of luminescent nanomaterials that have attracted considerable attention in recent years. They possess a range of exceptional physicochemical properties and ...

Bio & Medicine Jan 31, 2025

Green tea-derived nanosilver complex displays anti-melanoma activity

Melanoma is a fast-progressing skin cancer characterized by a high mortality rate after metastasis. Local chemotherapy could be considered a therapeutic approach only in stage 0 of progression (in situ melanoma) and in the ...

Bio & Medicine Jan 30, 2025

Surprising longevity of nanoparticle paste offers hope for surgery-sparing technique

A nanotechnology-based drug delivery system developed at UVA Health to save patients from repeated surgeries has proved to have unexpectedly long-lasting benefits in lab tests—a promising sign for its potential to help ...

Bio & Medicine Jan 24, 2025

Peptide-coated nanoparticles achieve 98% drug loading, improving cancer treatment

A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy, as demonstrated in leukemia models. ...

Bio & Medicine Jan 24, 2025

Q&A: Delivering gene therapy to the lung using nanoparticles

Ever since the gene responsible for cystic fibrosis was discovered 25 years ago, scientists have envisaged gene therapies to correct the underlying genetic defect.

Nanomaterials Jan 22, 2025

From soot particle filters to renewable fuels: Examining carbon nanoparticle oxidation

Carbon particles are present in many aspects of our daily lives. Soot, which consists of tiny carbon particles, is generated when energy sources such as oil or wood are not completely burned. Soot particle filters, in turn, ...

Bio & Medicine Jan 22, 2025

Proposed solution could bring DNA-nanoparticles motors up to speed with motor proteins

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion through enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical ...

Bio & Medicine Jan 16, 2025

Nanoparticles restore neurons in Parkinson's with wireless brain stimulation

Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction. Its pathological hallmark is the abnormal aggregation of α-synuclein (α-syn) into insoluble fibrils ...

Bio & Medicine Jan 10, 2025

Q&A: Researchers discuss lipid nanoparticle therapy to stop tumor growth and restore tumor suppression

Yang Zhang, Ph.D., and Jinjun Shi, Ph.D., both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a paper published in ...

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