The majority of RNAs in each of our cells don't code for any of the thousands of proteins that make up our bodies. Instead, noncoding RNAs have critical roles in many biological processes—such as gene expression—making ...
The human body and its organs are composed of a wide variety of cell types. Although all cells contain the same genes, they function very differently—partly because protein interactions differ between cells.
Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric ...
"Supply and demand" constraints limit the body's ability to produce the various proteins needed for critical life functions, according to a new study.
An AI tool has made a step forward in translating the language proteins use to dictate whether they form sticky clumps similar to those linked to Alzheimer's disease and around fifty other types of human disease. In a departure ...
Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, published in Nature Communications, shows promising results in animal studies ...
Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks into strands (or fibrils) ...
Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3. Findings show that LPD-3 contains ...
Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The specific location of each atom within the drug molecule is a critical factor in determining how well it ...
A joint research team has developed a modular protein adapter technology that enables the stable attachment of various substances to the surface of extracellular vesicles (exosomes). It was designed to enable functional molecules ...
