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Search results for therapeutic protein

Molecular & Computational biology Apr 17, 2025

'Time machine' enzyme could improve mRNA-based therapeutics

Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism that improves the efficiency of mRNA-based therapies. The research findings could facilitate the ...

Cell & Microbiology Apr 16, 2025

Scientists uncover novel function of autophagy protein ATG-9 in regulating lysosome integrity

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes play a vital role in maintaining ...

Cell & Microbiology Apr 16, 2025

Simulating protein structures involved in memory formation

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers from Japan have developed a computational model ...

Molecular & Computational biology Apr 16, 2025

New insights into protein-DNA interactions reveal cellular machinery secrets

New research pioneered by The University of Western Australia is shedding light on the intricate dance between proteins, DNA and RNA—the fundamental building blocks that carry out cellular processes and underpin all life, ...

Biotechnology Apr 14, 2025

'Molecular glues' offer a possible therapeutic approach for autoimmune conditions

Researchers have discovered a type of "molecular glue" that can be used to inhibit certain pathological protein interactions. Their findings were published in the paper, "Molecular glues that inhibit deubiquitylase activity ...

Cell & Microbiology Apr 3, 2025

Cellular regulator of mRNA vaccine revealed, offering new therapeutic options

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics.

Cell & Microbiology Apr 3, 2025

Jumbo phages infect cells with a protective cloaking mechanism, researchers discover

In a growing global trend, bacteria are evolving new ways to maneuver around medical treatments for a variety of infections. The rising antibiotic resistance crisis poses a significant public health threat in hospitals and ...

Cell & Microbiology Apr 3, 2025

Resolving a key to enterovirus infection: Receptor protein discovery could aid future vaccine design

Researchers found a protein that's essential for an enterovirus to enter human cells. Although not the infamous example—that title goes to poliovirus—other enteroviruses such as enterovirus D68 can cause similar paralytic ...

Cell & Microbiology Apr 2, 2025

DNA repair protein's unexpected structure may lead to new cancer treatments

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and mechanistic understanding of ...

Biotechnology Apr 2, 2025

Machine-learning algorithm hunts for brain-damaging proteins

A research group led by Gian Gaetano Tartaglia, Principal Investigator at the Italian Institute of Technology (IIT), developed a machine-learning algorithm to study the behavior of proteins within cells and to predict their ...

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