Q&A: Delivering gene therapy to the lung using nanoparticles
Ever since the gene responsible for cystic fibrosis was discovered 25 years ago, scientists have envisaged gene therapies to correct the underlying genetic defect.
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Ever since the gene responsible for cystic fibrosis was discovered 25 years ago, scientists have envisaged gene therapies to correct the underlying genetic defect.
Carbon particles are present in many aspects of our daily lives. Soot, which consists of tiny carbon particles, is generated when energy sources such as oil or wood are not completely burned. Soot particle filters, in turn, ...
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion through enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical ...
Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction. Its pathological hallmark is the abnormal aggregation of α-synuclein (α-syn) into insoluble fibrils ...
Yang Zhang, Ph.D., and Jinjun Shi, Ph.D., both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a paper published in ...
Researchers from POSTECH and Kyungpook National University have developed a novel inhalable therapeutic delivery system for lung cancer, leveraging mucoadhesive protein nanoparticles inspired by the adhesive properties of ...
A team of materials scientists, physicists, mechanical engineers, and molecular physiologists at Stanford University have developed a nanoparticle technique that can be used to measure force dynamics inside a living creature, ...
Researchers at Tel Aviv University have developed a new platform using polymeric nanoparticles to deliver drug pairs to specific cancer types, including skin cancer and breast cancer. The researchers explain that having both ...
Penn Engineers have made a critical breakthrough that bridges a major healthy equity gap for pregnant people with pre-eclampsia, a condition that arises due to insufficient blood flow to the placenta and results in high maternal ...
Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer and other diseases. However, the therapeutic effectiveness is limited by the poor translation uptake of naked mRNA. To circumvent this ...