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The immunosuppressive capacity of mesenchymal stem cells (MSCs) is dependent on the "license" of several proinflammatory factors to express immunosuppressive factors such as programmed cell death 1 ligand 1 (PD-L1), which ...
Bone marrow mesenchymal stromal cells (BMSCs) are the commonly used seed cells in tissue engineering. Aryl hydrocarbon receptor (AhR) is a transcription factor involved in various cellular processes. However, the function ...
Intervertebral disk degeneration (IDD) is a main contributor to low back pain. Oxidative stress, which is highly associated with the progression of IDD, increases senescence of nucleus pulposus-derived mesenchymal stem cells ...
Researchers at the Hong Kong University of Science and Technology (HKUST) have found how stem cells' surrounding environment controls them to differentiate into functional cells, a breakthrough critical for using stem cells ...
AMOLF researchers discovered that stem cells first specialize into a functional cell and then move to their proper location—rather than the other way around.
In a study published in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of ...
It has been widely acknowledged for a long time that mitochondrion is the main source of reactive oxygen species (ROS). The role of the endoplasmic reticulum (ER)-generated ROS has been less extensively studied. It has been ...
Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific ...
Mesenchymal stromal cells (MSCs) are multipotent cell populations obtained from fetal and adult tissues. They share some characteristics with limb bud mesodermal cells such as differentiation potential into osteogenic, chondrogenic, ...
Zinc (Zn) is the second most abundant trace element after Fe, present in the human body. It is frequently reported in association with cell growth and proliferation, and its deficiency is considered to be a major disease ...
