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Search results for extracellular matrix

Molecular & Computational biology Nov 12, 2021

Breaking down fungal biofilm defenses provides potential path to treating sticky infections

The microbes that make us sick often have ways to evade our attacks against them. Perhaps chief among these strategies is a sticky, armor-like goo, called the biofilm matrix, that encases clusters of disease-causing organisms.

Biotechnology Oct 28, 2021

Chemical-free cleaning of bioreactor membranes

Combining two chemical-free treatments shows promise as an approach for reducing biofilm build-up on anaerobic bioreactor membranes.

Bio & Medicine Oct 25, 2021

Using nanofibers to stop brain tumor cells from spreading

Brain cancer is difficult to contain and is often resistant to conventional treatment methods. Predicting tumor cell behavior requires a better understanding of their invasion mechanism. Now, researchers from University of ...

Bio & Medicine Oct 11, 2021

Bioinspired electromechanical nanogenerators to regulate cell activity

The extracellular matrix (ECM) including three-dimensional (3D) network and bioelectricity can profoundly influence cell development, migration, and functional expression. In a new report now published on Science Advances, ...

Cell & Microbiology Oct 7, 2021

Dysfunction in the mitochondrial respiration leads to cartilage degenerative diseases

A team led by Professor Dr. Bent Brachvogel, Head of Experimental Neonatology at the Faculty of Medicine and University Hospital Cologne, has discovered previously unknown regulatory mechanisms of tissue organization. Together ...

Cell & Microbiology Oct 1, 2021

Researchers shed new light on mechanical regulation of epithelial tissue homeostasis

An international team of scientists, led by Professor Ana-Sunčane Smith from the Croatian Ruđer Bošković Institute (RBI) and the Friedrich-Alexander University of Erlangen-Nürnberg in Germany, provided fresh insights ...

Bio & Medicine Aug 18, 2021

Bioresponsive micro-to-nano albumin-based systems for targeted drug delivery against complex fungal infections

As a typical human pathogenic fungus, Cryptococcus neoformansis a life-threatening invasive fungal pathogen with a worldwide distribution causing ∼700,000 deaths annually. Cryptococcosis is not just an infection with multi-organ ...

Evolution Jul 27, 2021

Genomic secrets of gutless deep-sea tubeworm unlocked

Researchers from The Hong Kong University of Science and Technology (HKUST) decoded for the first time the chromosomal-level genome of a deep-sea gutless tubeworm and how the worm's co-living bacterial partners manufacture ...

Cell & Microbiology Jul 20, 2021

Basement membrane underpins tissue interactions in the skin

In a discovery that could pave the way for therapies that promote wound healing and alleviate skin diseases, RIKEN researchers have found that the network of molecules under the outermost layer of mouse skin, the skin epithelium, ...

Bio & Medicine Jul 16, 2021

A noninvasive test to detect cancer cells and pinpoint their location

Most of the tests that doctors use to diagnose cancer—such as mammography, colonoscopy, and CT scans—are based on imaging. More recently, researchers have also developed molecular diagnostics that can detect specific ...

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