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Search results for genome editing

Molecular & Computational biology May 29, 2024

Researchers find RNA editing sites likely play a more significant role in genetic disease

New findings by University at Buffalo researchers reveal that RNA editing may play a larger role in human biology and in the development of human disease than has generally been understood.

Plants & Animals May 22, 2024

Research improves multiplex mutagenesis to increase experimental efficiency in plant genome editing

CRISPR/Cas9 remains the most powerful tool to generate mutations in plant genomes. Studying the various combinations of mutations has significantly increased the scale of experimental setups, necessitating more space to grow ...

Biotechnology May 20, 2024

A new chapter in grape cultivation: Non-transgenic plant regeneration technology

Traditional genome editing techniques encounter significant challenges in vegetatively propagated crops like grapes. Current transformation methods exhibit low efficiency and face difficulties in achieving stable plant regeneration ...

Biotechnology May 17, 2024

Researchers use machine-learning modeling tools to improve zinc-finger nuclease editing technology

Genome editing is making inroads into biomedical research and medicine. By employing biomolecule modeling tools, a Japanese research team is accelerating the pace and cutting the cost of zinc finger nuclease (ZFN) technology, ...

Biotechnology May 15, 2024

New strategy suppresses unwanted deletion events to make genome editing safer and more precise

A simple and robust strategy developed by KAUST scientists could help to improve the safety and accuracy of CRISPR gene editing, a tool that is already approved for clinical use for the treatment of inherited blood disorders.

Biotechnology May 10, 2024

Team develops efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict

A research group has constructed versatile genetic tools for Saccharolobus islandicus REY15A, one of the very few archaeal models for archaea biology and CRISPR biology research.

Cell & Microbiology May 9, 2024

For sustainable aviation fuel, researchers engineer a promising microorganism for precursor production

Sustainable aviation fuels made from renewable sources of carbon could reduce carbon dioxide emissions and help to mitigate climate change. Isoprenol is a chemical involved in the production of a jet biofuel blendstock called ...

Molecular & Computational biology May 9, 2024

Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation

Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory ...

Cell & Microbiology May 7, 2024

Microbiome studies help explore treatments for genetic disorders

A collaboration has led to the identification, in a bacterium of the intestine, of new CRISPR-Cas9 molecules that could have a clinical potential to treat genetic diseases such as retinitis pigmentosa, through sub-retinal ...

Biotechnology Apr 25, 2024

Advancing crop breeding through targeted genome modification

Modern crop breeding is entering a new era of genome design, led by genome editing technologies as mainstream tools for targeted genome modification.

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