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Materials Science Feb 21, 2021

Bioengineered hybrid muscle fiber for regenerative medicine

Muscle constitutes the largest organ in humans, accounting for 40% of body mass, and it plays an essential role in maintaining life. Muscle tissue is notable for its unique ability for spontaneous regeneration. However, in ...

Biochemistry Feb 16, 2021

New discovery may enable accurate prediction of cancer spread before cancer develops

Researchers from Erler Group at the Biotech Research & Innovation Centre (BRIC) in Copenhagen have discovered that the rigidity of a thin membrane structure encompassing cells and lining all vessels regulates how easily cancer ...

Bio & Medicine Feb 3, 2021

Researchers develop new method for biomanufacturing of vascularized tissue

Vascularized structures infiltrated within a nanofibrous extracellular matrix (ECM) play vital roles in maintaining functions and metabolism of tissue and organs. Nanofibrous scaffolds are promising in tissue engineering ...

Cell & Microbiology Jan 29, 2021

The force to shape an organ

Carnegie Mellon University professor of biomedical engineering and materials science and engineering Adam Feinberg, along with postdoctoral fellow Dan Shiwarski and graduate student Joshua Tashman, have created a novel biosensor ...

Cell & Microbiology Jan 26, 2021

Iron-carrying extracellular vesicles are key to respiratory viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report ...

Biochemistry Jan 25, 2021

Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum ...

Biotechnology Jan 18, 2021

Promoting axon regeneration in the zebrafish spinal cord

After an injury to the spinal cord, patients often remain paralyzed because damaged nerve tracts do not regrow due to the formation of scar tissue. Scientists from the Max Planck Institute for the Science of Light in Erlangen, ...

Cell & Microbiology Jan 12, 2021

New functions of integrin and talin discovered by an international research network

Researchers at Tampere University, Finland, have published new results in collaboration with an international research network that help to understand the biological phenomena mediated by cell membrane integrin receptors ...

Biochemistry Dec 31, 2020

Light-responsive E. coli functional biofilms as scaffolds for hydroxyapatite mineralization

Living organisms have evolved mechanisms of biomineralization to build structurally ordered and environmentally adaptive composite materials. While research teams have significantly improved biomimetic mineralization research ...

Biochemistry Dec 11, 2020

Hydrogel controls cell growth outside the body

Chemists at Radboud University discovered a unique material in 2013. From a synthetic polymer named polyisocyanopeptide (PIC), they made a gel that behaves similar to the matrix that surrounds the cells in your body. The ...

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