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Other Oct 9, 2024

Demis Hassabis, from chess prodigy to Nobel-winning AI pioneer

Long before Demis Hassabis pioneered artificial intelligence techniques to earn a Nobel prize, he was a master of board games.

Analytical Chemistry Oct 7, 2024

AI and quantum mechanics team up to accelerate drug discovery

Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit ...

Molecular & Computational biology Oct 1, 2024

3D structure of key protein could advance development of hormone-free male contraceptive pill

Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly ...

Biotechnology Sep 26, 2024

AI trained on evolution's playbook develops proteins that spur drug and scientific discovery

A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs ...

Biotechnology Sep 24, 2024

New AI tool efficiently deconvolutes compound-protein interactions

Compounds and proteins are the two most fundamental entities in drug discovery. Modeling their interactions is crucial for drug discovery. Although no universal computational method currently exists to predict and explain ...

Analytical Chemistry Sep 20, 2024

AI for drug discovery: DrugSynthMC to make finding new medication more efficient

Scientists have devised a free AI algorithm that they believe will make finding new medicines far more efficient.

Plants & Animals Sep 11, 2024

Four plants eaten by gorillas, also used in traditional medicine, provide clues for new drug discovery

Four plants consumed by wild gorillas in Gabon and used by local communities in traditional medicine show antibacterial and antioxidant properties, find Leresche Even Doneilly Oyaba Yinda from the Interdisciplinary Medical ...

Biotechnology Sep 11, 2024

Scientists expand the genetic alphabet to create new proteins

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words. But researchers trying to engineer biologic molecules ...

Cell & Microbiology Sep 9, 2024

Scientists learn how to drug wily class of disease-causing enzymes

UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable."

Cell & Microbiology Sep 4, 2024

Researcher helps develop new technique to explore oceanic microbes

When Southern Methodist University (SMU) researcher Alexander Chase was a young boy, the sheer diversity of plants in Earth's tropical rainforests fascinated him. He found himself wondering what new species were out there, ...

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