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Search results for organoids

Space Exploration Aug 26, 2021

Experiment to grow miniature human tissue on the International Space Station

The process for the joint 3D Organoids in Space project originated from the University of Zurich (UZH) researchers Oliver Ullrich and Cora Thiel. Together with Airbus, the two pioneers in research on how gravity affects and ...

Cell & Microbiology Aug 9, 2021

New CRISPR/Cas9 technique corrects cystic fibrosis in cultured human stem cells

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells. In collaboration with the UMC Utrecht and Oncode Institute, they used a technique ...

Cell & Microbiology Aug 2, 2021

Organoid bladders reveal secrets of UTIs

Urinary tract infections (UTIs) are among the most common bacterial infections. They usually require treatment with antibiotics, and almost a quarter of treated cases lead to recurrent infection. The vast majority of UTIs ...

Molecular & Computational biology Jul 8, 2021

Stem cells can use same method as plants and insects to protect against viruses

Researchers at the Francis Crick Institute have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. ...

Cell & Microbiology Jun 21, 2021

Researchers discover how the intestinal epithelium folds and moves by measuring forces

An international team led by Xavier Trepat at IBEC measures the cellular forces in mini-intestines grown in the laboratory, deciphering how the inner wall of this vital organ folds and moves. The study, published in Nature ...

Cell & Microbiology Jun 21, 2021

How do developing spinal cords choose 'heads' or 'tails'?

The progression from a round ball of cells to an embryo with a head and a tail is one of the most critical steps in an organism's development. But just how cells first start organizing themselves with directionality along ...

Cell & Microbiology Jun 8, 2021

Tracking RNA through space and time

The "miracle of life" is most obvious at the very beginning: When the fertilized egg cell divides by means of furrows into blastomeres, envelops itself in an amniotic sac, and unfolds to form germ layers. When the blastomeres ...

Biotechnology May 13, 2021

Teaching a computer program to track cells

Following the minuscule movements of every cell in a petri dish would be a painstaking task for any human. But teach a set of computer programs to do the job, and they can complete it quickly and even observe things that ...

Materials Science May 12, 2021

Scientists pioneer creation of programmable artificial tissues from synthetic cells

Scientists have created new artificial tissues that mimic some of the complex characteristics and abilities of living tissues, paving the way toward unprecedented advances in medicine, soft-robotics, and micro-engineering. ...

Cell & Microbiology May 6, 2021

To be or not to be: An organoid

Mini-organs, or organoids, play a big role in the future of medicine. Their countless applications can help develop and implement tailored therapies for each patient. The revolutionary development of organoids started in ...

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