In a study published in PNAS, a research team has resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c variants for disease theranostics ...
Bacterial biofilm infections are among the leading causes of morbidity and mortality among patients with cystic fibrosis or those with weakened immune systems. Treatment for biofilm infections usually entails intensive antibiotic ...
Breast cancer is the most common malignancy in women, posing a serious threat to female health. Due to the high inter- and intra-tumoral heterogeneity of breast cancer, clinical treatment and prognosis can vary greatly in ...
If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic ...
Recently, a research team led by Prof. Wu Zhengyan from Hefei Institutes of Â鶹ÒùÔºical Science, Chinese Academy of Sciences, in collaboration Binzhou Medical University, successfully designed a nanostructure that improves the ...
When it comes to delivering drugs to the body, a major challenge is ensuring that they remain in the area they're treating and continuing to deliver their payload accurately. While major strides have been made in delivering ...
Upconversion (UC) luminescence is a process that converts low-energy photons into higher-energy ones with promising applications in diverse fields. However, known UC mechanisms mainly focus on the energy transfer processes ...
Â鶹ÒùÔºicians and researchers rely on biomedical imaging to examine the structure and function of living tissue. This enables disease diagnostics and experiments that reveal the mechanisms behind pathologies and ways to treat ...
Fluorescence-guided intervention strategies can improve standard therapies to detect and treat microscopic tumors to thereby prevent lethal recurrence. Cancer biologists have made tremendous progress in photoimmunotherapy ...
Atherosclerosis is characterized by the hardening of blood vessels, especially certain arteries, due to the local buildup of fibers and lipids (mainly cholesterol) in the inner wall of an artery, causing it to narrow. It ...
