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Search results for therapeutic protein

Biochemistry Jan 6, 2025

Scientists create vast library of compounds to target disease proteins

Over the past two decades, large genetic studies have linked tens of thousands of DNA variants to thousands of human traits and diseases. Yet, correcting the effects of those variants to treat disease has been hampered in ...

Cell & Microbiology Jan 6, 2025

Membrane anchor suppresses protein aggregation in neurodegenerative diseases, modeling study shows

Protein aggregation is typical of neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team headed by Professor Jörg Tatzelt from the Department of Biochemistry ...

Bio & Medicine Dec 24, 2024

AI-designed 'nanocages' mimic viral behavior for enhanced gene therapy

Researchers have developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence (AI). Their pioneering research was published in Nature on December 18.

Bio & Medicine Dec 23, 2024

Biodegradable nanoparticles enable simultaneous delivery of two drugs to attack tumors

Researchers at Tel Aviv University have developed a new platform using polymeric nanoparticles to deliver drug pairs to specific cancer types, including skin cancer and breast cancer. The researchers explain that having both ...

Cell & Microbiology Dec 10, 2024

Weaponizing bacterial viruses to combat superbugs

Researchers from the University of Illinois have reported complementary discoveries that will improve scientists' understanding of immune systems in bacteria and equip clinicians with more effective options for treating antibiotic-resistant ...

Cell & Microbiology Dec 10, 2024

Toxoplasma gondii parasite uses unconventional method to make proteins for evasion of drug treatment, research reveals

A study by Indiana University School of Medicine researchers sheds new light on how Toxoplasma gondii parasites make the proteins they need to enter a dormant stage that allows them to escape drug treatment. The research ...

Bio & Medicine Dec 9, 2024

Delivering mRNA and RNAi-based therapies in single treatment could combat complex diseases

Researchers at the University of Ottawa may have cracked the code to harness both mRNA and RNAI-based therapies to improve the treatment of cancer, cardiovascular and other complex diseases.

Bio & Medicine Dec 9, 2024

Novel mixture of mRNA in nanoparticles show therapeutic potential against tumor progression

Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer and other diseases. However, the therapeutic effectiveness is limited by the poor translation uptake of naked mRNA. To circumvent this ...

Biotechnology Dec 5, 2024

Spectroscopy and AI method provide unique window into protein structure and mechanism of action

The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological blueprint that couples experimental ...

Molecular & Computational biology Dec 5, 2024

Protein engineering research reveals the mysteries of life, enabling advances in pharmaceuticals

Proteins are so much more than nutrients in food. Virtually every reaction in the body that makes life possible involves this large group of molecules. And when things go wrong in our health, proteins are usually part of ...

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