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Search results for extracellular matrix

Molecular & Computational biology Dec 11, 2020

Expression, diffusion and molecular interactions determine Wnt3 distribution

An interdisciplinary team of physicists and biologists from NUS has characterized the mechanism by which Wnt3, a key regulator in neural patterning and brain development, spreads to long distances in the developing zebrafish ...

Cell & Microbiology Dec 10, 2020

Embryonic development in a petri dish: 3-D cell culturing technique could replace mouse embryos

By growing mouse stem cells in a special gel, a Berlin research team succeeded in producing structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle ...

Cell & Microbiology Dec 1, 2020

Watch immune cells dig tunnels in tissues

White blood cells called cytotoxic T lymphocytes (CTLs) dig tunnels in tissues, potentially allowing other CTLs to quickly reach infected cells and tumor cells, researchers report December 1st in Biophysical Journal. The ...

Biochemistry Nov 30, 2020

Recombinant collagen polypeptide as a versatile bone graft biomaterial

The current gold standard for bone grafting surgery includes autografts and allografts, although a growing demand exists to develop synthetic biomaterials for enhanced bio-integration in bone tissue engineering. In a new ...

Space Exploration Nov 25, 2020

Fruit flies reveal new insights into space travel's effect on the heart

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that fruit flies that spent several weeks on the International Space Station (ISS)—about half of their lives—experienced profound structural ...

Materials Science Nov 18, 2020

Algae breathe life into 3-D engineered tissues

3-D bioprinted algae can be harnessed as a sustainable source of oxygen for human cells in engineered vascularized tissues, researchers report November 18 in the journal Matter. They embedded the bioprinted photosynthetic ...

Cell & Microbiology Nov 9, 2020

Researchers elucidate the mechanics of cellular attachment

For cells to assemble into tissues and whole organs, the extracellular matrix (ECM) as well as integrins are required. The ECM forms a kind of extra-cellular protein meshwork; the integrins are surface proteins, which cells ...

Biotechnology Oct 29, 2020

A groundbreaking genetic screening tool for human organoids

Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly Drosophila and the nematode C. elegans, ...

Cell & Microbiology Oct 8, 2020

Mechanical forces of biofilms could play role in infections

The vast majority of bacteria in the world live on surfaces by forming structures called biofilms. These communities host thousands to millions of bacteria of different types, and are so biologically complex and active that ...

Bio & Medicine Sep 30, 2020

Nanomotors as probes to sense cancer environment

An interdisciplinary team of researchers from the Indian Institute of Science (IISc) has used a 3-D tumor model and magnetically driven nanomotors to probe the microenvironment of cancer cells. The team consists of researchers ...

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