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Search results for genome editing

Biochemistry Oct 5, 2023

Precise genome engineering and protein activity profiling uncover new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs ...

Biotechnology Sep 29, 2023

Newly engineered CRISPR enzyme for editing DNA could improve patient treatment

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but ...

Cell & Microbiology Sep 29, 2023

Using a cutting enzyme and an RNA repair enzyme to modify RNA virus genomes

A team of microbiologists at Montana State University has developed a way to use a cutting enzyme and an RNA repair enzyme to modify the genome of an RNA virus. They describe their technique in Science Advances.

Biotechnology Sep 21, 2023

Split gene-editing tool offers greater precision

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule is added.

Cell & Microbiology Sep 15, 2023

Study examines the hard reality that no pollen means no seeds

North Carolina State University researchers have successfully transferred an important gene from one compartment of a plant cell to another to produce tobacco plants that lack pollen and viable seeds, while otherwise growing ...

Biotechnology Sep 15, 2023

A NICER approach to genome editing

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...

Biotechnology Sep 1, 2023

Researchers make genome prime editors smaller and more efficient for therapeutic applications

Prime editing technologies allow scientists to precisely edit the genome in a variety of ways and could one day be used to treat genetic diseases. Now researchers at the Broad Institute of MIT and Harvard have used cutting-edge ...

Cell & Microbiology Aug 30, 2023

A DNA assembly kit to unlock the CRISPR-Cas9 potential for metabolic engineering

The clustered regularly interspaced short palindrome repeats (CRISPR) and Crispr-associated protein 9 (CRISPR/Cas9) is now a well-known, revolutionary method to engineer microbial cells.

Biotechnology Aug 29, 2023

Geneticists develop novel base editors

In a study published in Nature Biotechnology on Aug. 28, Gao Caixia's group at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences and her collaborators at Qi Biodesign have reported a modular, ...

Biotechnology Aug 24, 2023

New gene-editing technique offers path to precision therapies

PNP editing is emerging as a versatile and programmable tool for site-specific DNA manipulations. An innovative genome-editing technique could enhance the delivery, specificity and targeting of gene-modifying tools for treatments.

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