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Biotechnology Dec 14, 2023

Scientists create artificial DNA that can be transcribed by a natural enzyme

The genetic alphabet contains just four letters, referring to the four nucleotides, the biochemical building blocks that comprise all DNA. Scientists have long wondered whether it's possible to add more letters to this alphabet ...

Plants & Animals Dec 13, 2023

Scientists identify biosynthetic pathway of chemotherapeutic derived from yew trees

Researchers from the Max Planck Institute of Molecular Plant Âé¶¹ÒùÔºiology have unraveled the biosynthetic pathway of paclitaxel in yew plants, a chemotherapeutic for cancer treatment. This discovery might facilitate the production ...

Biotechnology Dec 11, 2023

Unlocking the secrets of synthetic biology: Host physiology over phylogeny in genetic circuit performance

Broad host range (BHR) synthetic biology aims to capitalize on a wide range of microbial phenotypes to expand biodesign applications not confined to traditional model organisms. Despite the ever-expanding genetic toolkit, ...

Biotechnology Dec 11, 2023

Decoding plant gene expression: A deep dive into promoters and terminators for advanced bioengineering

In high-precision bioengineering and synthetic biology, the fine-tuning of gene expression at transcriptional and posttranscriptional levels is essential. This involves a detailed understanding and manipulation of promoters ...

Cell & Microbiology Dec 7, 2023

Cracking 6mA code to enhance lipid accumulation in microalgae

Microalgae—which are major contributors to global photosynthesis and primary productivity—serve as promising chassis cells in synthetic biology.

Biochemistry Dec 6, 2023

Engineering customizable bio-adhesives for personalized medical repair

Traditional medical adhesives used in surgical applications often have limited bio-absorbability, high toxicity and a lack of customizability, leading to suboptimal surgical outcomes. Recent advances in synthetic biology ...

Cell & Microbiology Dec 5, 2023

Revolutionizing biorefineries: Advancing toward sustainable third-generation technologies in COâ‚‚ utilization

The evolution of biorefineries, shifting from sugar-based and biomass feedstocks to third-generation (3G) technologies, marks significant progress toward sustainable development. 3G biorefineries use microbial cell factories ...

Cell & Microbiology Dec 5, 2023

Ice cores as a source for antimicrobials: From bioprospecting to biodesign

In November 2023, BioDesign Research published a perspective article titled "Ice Cores as a Source for Antimicrobials: From Bioprospecting to Biodesign," outlining a revolutionary approach to antibiotic discovery using ice ...

Biochemistry Dec 5, 2023

Breakthrough in the synthesis of artificial cells

A study published in Nature Chemistry reveals a remarkable leap in the synthesis of artificial cells using synthetic materials, which was achieved by an international team led by Dr. Andrea Belluati, Prof. Nico Bruns (both ...

Molecular & Computational biology Dec 4, 2023

Pioneering the future: An innovative approach to plant synthetic genomics

In October 2023, BioDesign Research published a perspective article titled "Toward Synthetic Genomics in Plants." Focusing on the emerging field of plant synthetic genomics, this study delves into the complexity of assembling ...

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