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Search results for therapeutic protein

Cell & Microbiology Aug 28, 2024

New research elucidates a master regulator of protein production

Proteins are among the most important molecular building blocks of life. They themselves are built from amino acids linked together based on the information in our genetic material. In this process, the genetic code is translated ...

Biotechnology Aug 26, 2024

Closing the RNA loop holds promise for more stable, effective RNA therapies

New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego. The advance holds promise for a range of diseases, ...

Molecular & Computational biology Aug 22, 2024

New models help predict protein dynamic signatures

To the average person, knowing how a protein wiggles might not seem that exciting or pertinent, but then again, most people aren't fascinated by the natural movements and fluctuations of proteins and their functional properties. ...

Biochemistry Aug 19, 2024

Biochemists engineer proteins that can transition between assembly and disassembly via allosteric control

A team of biochemists at the University of Washington has developed a means for engineering proteins that can transition between assembly and disassembly via allosteric control. In their paper published in the journal Nature, ...

Cell & Microbiology Aug 16, 2024

Newly discovered mechanism for propagation of flaviviruses reveals potential therapeutic target

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and tick-borne encephalitis virus, are significant arthropod-borne pathogens. ...

Molecular & Computational biology Aug 12, 2024

Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme

Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed ...

Cell & Microbiology Aug 10, 2024

A common parasite could deliver drugs to the brain—how scientists are turning Toxoplasma gondii from foe into friend

Parasites take an enormous toll on human and veterinary health. But researchers may have found a way for patients with brain disorders and a common brain parasite to become frenemies.

Biochemistry Aug 9, 2024

New method enables gradual release of protein drugs into the body

Therapeutic proteins have been increasingly used in recent years to treat cancer, HIV, and other diseases. A challenge with these types of drugs is that the release is rapid and thus the medicine must be administered frequently.

Biotechnology Aug 5, 2024

Novel siRNA backbone enhances stability, durability of oligonucleotide therapeutic platform

A biochemical breakthrough using simple carbon atoms, by Ken Yamada, Ph.D., and Anastasia Khvorova, Ph.D., has dramatically improved the stability and efficacy of a potential oligonucleotide therapeutic platform in mice. ...

Biotechnology Aug 2, 2024

Scientists 'cautiously optimistic' about AI's role in drug discovery

The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its ...

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