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Cell & Microbiology Jun 15, 2022

The new heroics of RNA in cell differentiation

Scientists are increasingly learning of new reasons to appreciate RNA, and the glycolytic enzyme ENO1 seems to have provided yet another in new research from EMBL this week, as published in Molecular Cell.

Cell & Microbiology Jun 14, 2022

New method for cell sorting utilizing microRNA switch and magnetic microbeads

The group led by Drs. Yoshinori Yoshida and Hirohide Saito succeeded in collecting and purifying large amounts of iPS cell-derived cardiomyocytes rapidly with the technology they newly developed by combining a cell sorting ...

Plants & Animals Jun 14, 2022

Researchers isolate germline stem cells in protogynous hermaphroditic Monopterus albus

Germline stem cells (GSCs), originating from primordial germ cells (PGCs) during embryogenesis, are a group of unique adult stem cells in gonads that are essential to genetic information transfer.

Cell & Microbiology Jun 9, 2022

Researchers use biomolecule-loaded metal-organic frameworks nanopatterns to aid artificial stem cell differentiation

Stem cells are essentially our body's raw materials—cells that give rise to all other cells and tissues with specialized functions. The conversion into specific cells occurs through a process called "differentiation," in ...

Cell & Microbiology Jun 9, 2022

Maintaining the right niche for blood cell development

In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them. Within the body, hematopoietic stem cells (HSCs) reside in their ...

Cell & Microbiology Jun 8, 2022

Ketogenic diet helps mouse muscle stem cells survive stress, study finds

Fasting sends muscle stem cells into a deep resting state that slows muscle repair but also makes them more resistant to stress, according to a Stanford Medicine study of laboratory mice.

Cell & Microbiology May 27, 2022

Researchers unravel role of cohesins in embryonic stem cell division

Chromosomes undergo precise structural changes at a molecular level during the different phases of cell division. These changes occur at a high level of accuracy to prevent genome instability. Genome instability resulting ...

Cell & Microbiology May 16, 2022

Mouse stem cells for primitive endoderm established

Stem cells that give rise to the mouse yolk sac have been isolated and cultured in the lab for the first time by RIKEN researchers, raising the possibility of artificially creating mouse embryos from stem cells in the future.

Molecular & Computational biology Apr 29, 2022

Study identifies how blood stem cells maintain their fate

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical ...

Cell & Microbiology Apr 27, 2022

Cilia-free stem cells offer new path to study rare diseases

A group of rare diseases called "ciliopathies"—polycystic kidney disease notable among them—emerge from defects in cilia, the tiny hair-like structures on the surface of almost every cell type. But the specific molecular-level ...

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