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Search results for drug discovery

Biochemistry Feb 21, 2024

New class of 'intramolecular bivalent glue' could transform cancer drug discovery

A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.

Cell & Microbiology Feb 21, 2024

Learning how cells dispose of unwanted materials is key to potential new therapeutics, say scientists

Are you sick and tired of getting sick and tired? A UNLV-led research team is exploring whether the reason we sometimes feel ill in the first place is because our body's cells suffer from trash that accumulates within them.

Analytical Chemistry Feb 20, 2024

Research team develops universal and accurate method to calculate how proteins interact with drugs

A research team from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague has developed a novel computational method that can accurately describe how proteins interact with molecules ...

Biotechnology Feb 16, 2024

Belgian researchers provide a strong boost to sustainable agriculture

Much has been written about the European Climate law and the European Nitrate Directive. Besides social concerns, drastically reducing greenhouse gases by 2030 and structurally lowering the use of nitrogen in agriculture ...

Biochemistry Feb 15, 2024

Superbug killer: New synthetic molecule highly effective against drug-resistant bacteria

A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

Biochemistry Feb 14, 2024

Discovery of new plant protein fold may be seed for anti-cancer drugs

University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging ...

Molecular & Computational biology Feb 14, 2024

AI tool predicts function of unknown proteins

A new artificial intelligence (AI) tool that draws logical inferences about the function of unknown proteins promises to help scientists unravel the inner workings of the cell.

Space Exploration Feb 12, 2024

Astronauts from NASA's Expedition 71 to conduct research aboard space station

Studies of neurological organoids, plant growth, and shifts in body fluids are among the scientific investigations that NASA astronauts Matthew Dominick, Michael Barratt, Jeanette Epps, and Tracy C. Dyson will help support ...

Biotechnology Feb 8, 2024

New research with implications for drug discovery makes it possible to visualize the smallest protein clusters

Penn Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases ...

Biochemistry Jan 30, 2024

New drug reveals a key mechanism to overcome resistance to protein degraders

Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...

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