Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter ...
Australian researchers, led by Monash University, have invented a new artificial intelligence (AI) tool which is poised to reshape virtual screening in early stage drug discovery and enhance scientists' ability to identify ...
A Dartmouth study conducted on fruit flies reports the first evidence in any organism that oocytes—the cells that become eggs—regularly rejuvenate the critical protein linkages that bind chromosomes together. The findings ...
Essential oils, also known as ethereal oils, are volatile, aromatic compounds derived from plants. Found in only about 10% of the plant kingdom, these oils are present in secretory structures such as glands, ducts, cavities, ...
Mass production of recombinant proteins using yeast cell "factories" needs methanol, a compound that requires safe handling, carries the risk of catching fire, and sometimes produces harmful byproducts. Researchers at the ...
Proteins are vital biomolecules responsible for performing various functions in the human body and are thus regarded as the workhorses of a cell. The primary structure of a protein is composed of different amino acids coming ...
In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison ...
An interdisciplinary collaboration has designed a way to "cloak" proteins so that they can be captured by lipid nanoparticles, which are akin to tiny bubbles of fat. These bubbles are small enough to sneak their hidden cargo ...
Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as ...
It is known that malfunctions of the proteins FLVCR1 and FLVCR2 lead to rare hereditary diseases in humans that cause motor, sensory and neurological disorders. However, the biochemical mechanisms behind this and the physiological ...
