A new way to deliver drugs using a common protein could be used to develop mosaic vaccines, which are vaccines effective against multiple strains of a virus like COVID-19, among other medicines in a global first.
The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, conventional delivery methods have several limitations.
A review delves into the significance of biomolecular condensation in cellular processes, the impact of aberrant phase separation on diseases such as neurodegenerative diseases, cancers, and infectious diseases, and the potential ...
Artificial intelligence (AI) has numerous applications in health care, from analyzing medical imaging to optimizing the execution of clinical trials, and even facilitating drug discovery.
Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer ...
Antibiotic medicines became a popular treatment for bacterial infections in the early 20th century and emerged as a transformational tool in human health. Through the middle of the century, novel antibiotics were regularly ...
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases, enzymes commonly used ...
The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect other ions and proteins ...
Understanding how proteins interact with each other is crucial for developing new treatments and understanding diseases. Thanks to computational advances, a team of researchers led by Assistant Professor of Chemistry Alberto ...
