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Search results for therapeutic protein

Biotechnology Apr 10, 2024

New protein imaging method supports the design of innovative new cancer drugs

Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was ...

Biochemistry Apr 10, 2024

A promising target for new RNA therapeutics now accessible

Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's ...

Cell & Microbiology Apr 4, 2024

'Force-sensing' protein could better treat diseases that cause seizures

Researchers from The Australian National University (ANU) have made a discovery about a little understood protein in the human body that could help treat diseases that cause seizures, including epilepsy. The study is published ...

Cell & Microbiology Apr 3, 2024

New tools reveal how genes work and cells organize

Researchers from Aarhus University and the Italian Institute of Technology have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational ...

Molecular & Computational biology Mar 25, 2024

Study describes structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP

A recent article in the journal Nature Communications describes the structural basis of mimicked HBV/HDV viral peptide drug interaction with its receptor NTCP.

Cell & Microbiology Mar 22, 2024

Researchers devise new way to find proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins—a new but largely unrealized approach to the treatment ...

Biotechnology Mar 22, 2024

Messenger RNAs with multiple 'tails' could lead to more effective therapeutics, say researchers

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, ...

Biotechnology Mar 15, 2024

Scientists generate new targeted protein degradation system that tunes a cell's own proteins

Researchers studying the role of proteins in health and disease use experimental tools that inactivate proteins, destroy them, or prevent them from being made in cells. In one approach, they mark targeted proteins with "destroy ...

Biotechnology Mar 14, 2024

New bioengineered protein design shows promise in fighting COVID-19

In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat ...

Biochemistry Mar 13, 2024

New computational strategy boosts the ability of drug designers to target proteins inside the membrane

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed ...

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