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Search results for therapeutic protein

Analytical Chemistry Sep 27, 2023

Team develops key improvement to cryo-electron microscopy

The scientists who received the 2017 Nobel Prize in chemistry were honored for their development of a technique called cryo-electron microscopy, or cryo-EM. The technology was revolutionary because it enabled scientists to ...

Bio & Medicine Sep 25, 2023

Researchers pioneer safe nanocarrier system for treating bacterial infections

Antibiotic resistant bacteria are a threat to human lives, and yet the development of new drugs to treat bacterial infections is slow. A group of proven drugs used in cancer treatment for decades could possibly be the solution. ...

Molecular & Computational biology Sep 14, 2023

Researchers enhance the function of natural proteins using 'protein Legos'

Johns Hopkins engineers have helped develop and characterize an artificial protein that triggers the same response in the human body as its natural counterpart—a breakthrough that not only has the potential to facilitate ...

Molecular & Computational biology Sep 14, 2023

Researchers discover tissue-specific protection against protein aggregation

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation ...

Biotechnology Sep 1, 2023

Researchers make genome prime editors smaller and more efficient for therapeutic applications

Prime editing technologies allow scientists to precisely edit the genome in a variety of ways and could one day be used to treat genetic diseases. Now researchers at the Broad Institute of MIT and Harvard have used cutting-edge ...

Cell & Microbiology Aug 28, 2023

A synthetic RNA export system reveals the dynamic lives of cells and suggests direction for new therapeutics

Cells change dynamically over time during embryonic development and aging, and in diseases such as inflammation and cancer. Some populations expand, others decline. The ability to track these changes over time, without killing ...

Cell & Microbiology Aug 23, 2023

Learning from viruses: Molecular fibers can help to introduce genetic material into cells

Pathogenic viruses that enter the human body can dock onto cells with their tentacle-like extensions, whereupon the cell takes up the viruses. This process, which is already known and occurs in diseases such as HIV, can also ...

Biotechnology Aug 23, 2023

Researchers design switch-like proteins inspired by transistors

Scientists from the University of Washington have designed custom proteins that can switch between two fully structured conformations. By coupling this molecular motion with a binding event, these proteins serve as biological ...

Bio & Medicine Aug 18, 2023

Sniffing nanoparticles loaded with mRNA could lead to advanced lung therapeutics

Researchers at Yale University, New Haven, have optimized a polymer-based mRNA vehicle for targeted lung delivery and demonstrated the potential of the platform for mucosal vaccination against respiratory pathogens.

Cell & Microbiology Aug 17, 2023

Molecule identified that could be key for a new wave of drugs to target obesity and bone diseases

Scientists have identified a molecule that plays a key role in how cells detect when they are being pushed or pulled which could lead to the development of future drugs for obesity, osteoporosis, and inflammatory diseases.

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