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Biochemistry Apr 7, 2023

Birch reduction simplified to a one-minute mechanochemical process

The traditionally cumbersome yet widely-used Birch reduction can now be carried out in a mere minute in air using an optimized mechanochemical approach.

Bio & Medicine Apr 6, 2023

Super-sized nanocage could deliver bigger drug cargoes

Think about how frustrating it is to try to fit a gift into a box that is too small. Sometimes you just need a bigger box.

Biochemistry Mar 31, 2023

Speeding up drug discovery with diffusion generative models

With the release of platforms like DALL-E 2 and Midjourney, diffusion generative models have achieved mainstream popularity, owing to their ability to generate a series of absurd, breathtaking, and often meme-worthy images ...

Analytical Chemistry Mar 28, 2023

Advancing drug discovery through multitask learning techniques

A team of researchers from the Skolkovo Institute of Science and Technology, the University of Vienna, and Sirius University of Science and Technology has published a study in the Journal of Computer-Aided Molecular Design ...

Biotechnology Mar 28, 2023

Developing drugs against drought

Abscisic acid (ABA) is a plant hormone with essential functions in plant physiology. It is involved in developmental and growth processes and the adaptive stress response. Thus, the plant adaptation to stress situations caused ...

Biochemistry Mar 28, 2023

Discovery of drug candidate that neutralizes SARS-CoV-2 could reduce length of infection upon exposure

The discovery of a small molecule in the research lab of Bradley McConnell, professor of pharmacology at the University of Houston College of Pharmacy, may well be the genesis of new medication which could shorten the course ...

Biochemistry Mar 16, 2023

Protein engineers navigate toward more targeted therapeutics

More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate ...

Cell & Microbiology Mar 13, 2023

A novel biosensor to detect DNA damage in real time

Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...

Biochemistry Mar 10, 2023

Biochemical synthesis discovery could unlock new drug development breakthroughs

A mystery about how a chemical compound found in nature could be synthesized in the lab may have been solved, scientists say—a breakthrough that could unlock new developments in medicine.

Space Exploration Mar 9, 2023

3D bioprinter to print human meniscus on the space station

The knee is not only one of the largest and most complex joints in the body—it is also easily injured. In fact, one of the most common orthopedic injuries is the tearing of the meniscus, a half-moon-shaped piece of cartilage ...

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