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Cell & Microbiology Mar 13, 2023

A novel biosensor to detect DNA damage in real time

Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...

Biochemistry Mar 10, 2023

Biochemical synthesis discovery could unlock new drug development breakthroughs

A mystery about how a chemical compound found in nature could be synthesized in the lab may have been solved, scientists say—a breakthrough that could unlock new developments in medicine.

Space Exploration Mar 9, 2023

3D bioprinter to print human meniscus on the space station

The knee is not only one of the largest and most complex joints in the body—it is also easily injured. In fact, one of the most common orthopedic injuries is the tearing of the meniscus, a half-moon-shaped piece of cartilage ...

Biochemistry Mar 9, 2023

Using peptides instead of DNA to tag molecules to speed up drug discovery

A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.

Bio & Medicine Mar 7, 2023

Brain tumor discovery paves way for new drug treatments

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and ...

Nanophysics Mar 6, 2023

An innovative twist: Tubular nanomaterial of carbon makes ideal home for spinning quantum bits

Scientists are vigorously competing to transform the counterintuitive discoveries about the quantum realm from a century past into technologies of the future. The building block in these technologies is the quantum bit, or ...

Biochemistry Feb 28, 2023

Effective method to avoid activating a cellular detoxification receptor to overcome drug resistance and toxicity

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance. The researchers made slight changes to a small molecule to reduce its metabolism and ...

Analytical Chemistry Feb 24, 2023

PanGu drug model: Learn a molecule like a human

A recent study published in the journal Science China Life Sciences was led by Dr. Nan Qiao (Laboratory of Health Intelligence, Huawei Cloud Computing Technologies), Dr. Hualiang Jiang (Shanghai Institute of Materia Medica, ...

Cell & Microbiology Feb 23, 2023

MoBIE enables modern microscopy with massive data sets

High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination of such large imaging data sets poses significant ...

Biochemistry Feb 23, 2023

New human antibody neutralizes snake neurotoxins across species and geographies

Snakes bite 5.4 million people each year—and roughly half are injected with venom, according to the WHO. Between 81,000 and 138,000 people die, while around three times as many suffer amputations and other permanent disabilities. ...

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