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Search results for genome editing

Plants & Animals Feb 17, 2022

CROPSR: A new tool to accelerate genetic discoveries in crops

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) should accelerate their development—as well ...

Biotechnology Feb 15, 2022

Gene editing now possible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field. The work appears ...

Molecular & Computational biology Feb 9, 2022

Advancing genome editing through studying DNA repair mechanisms

Since the discovery of CRISPR/Cas9, also known as molecular scissors, scientists around the world have been working to improve the revolutionary technique for altering DNA that earned Emmanuelle Charpentier and Jennifer Doudna ...

Molecular & Computational biology Feb 9, 2022

Leveraging multiplex genome editing to create disease-resistant wheat

In a study published online in Nature, Chinese scientists have described their use of genome editing to achieve robust disease resistance without any growth defects. This achievement represents an important theoretical and ...

Molecular & Computational biology Feb 8, 2022

We've decoded the numbat genome – and it could bring the thylacine's resurrection a step closer

It used to be the stuff of science fiction: bringing a long-dead species back from extinction by painstakingly piecing together its full DNA sequence, or genome.

Biotechnology Feb 8, 2022

Study in mice shows potential for gene-editing to tackle mitochondrial disorders

Defective mitochondria—the 'batteries' that power the cells of our bodies—could in future be repaired using gene-editing techniques. Scientists at the University of Cambridge have shown that it is possible to modify the ...

Cell & Microbiology Jan 24, 2022

Landing therapeutic genes safely in the human genome

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...

Biotechnology Jan 24, 2022

Clearer distinction needed between GMOs and genome-edited organisms

Researchers from Hokkaido University have proposed a framework to assist in the demarcation between genetically modified organisms and genome-edited organisms, taking into account both scientific and socio-ethical considerations.

Molecular & Computational biology Jan 19, 2022

Discovery of a 'hidden gem' enables gene editing with a small but mighty CRISPR-Cas3 system

Nearly a decade ago, scientists discovered the power of CRISPR, a tool employed by bacteria to protect themselves against viral invaders. This system is now a fundamental research tool used for editing genomes. One of most ...

Cell & Microbiology Jan 19, 2022

Comprehensive detection of on- and off-target mutations

Sometimes the smallest action can have unintended consequences, like the proverbial flap of a butterfly's wings. So, when making small changes, it's important to be alert to large effects, such as when using gene editing ...

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