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Search results for genome editing

Cell & Microbiology Jan 12, 2022

Engineered particles efficiently deliver gene editing proteins to cells in mice

Gene editing approaches promise to treat a range of diseases, but delivering editing agents to cells in animal models and humans safely and efficiently has proven challenging. Now, researchers led by a team at the Broad Institute ...

Molecular & Computational biology Dec 28, 2021

Researchers develop specific and sensitive Cas12c-based nucleic acid detection platform

The prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated (CRISPR/Cas) protein system has been reconstructed for a revolutionary targeted genome modification platform and nucleic ...

Molecular & Computational biology Dec 23, 2021

Translocation on chromosome 6 causes abnormalities during meiosis and fewer seeds in watermelon

Watermelon (Citrullus lanatus) is an economically important horticultural crop and one of the top five most widely consumed fresh fruits in the world. Compared with traditional seeded cultivars, seedless watermelon is preferred ...

Cell & Microbiology Dec 21, 2021

Genes are switched on in the human embryo from the get-go

The finding that some genes are active from the get-go challenges the textbook view that genes don't become active in human embryos until they are made up of four-to-eight cells, two or three days after fertilization.

Plants & Animals Dec 20, 2021

Cotton genome study bound for International Space Station

Clemson researcher Chris Saski admits sending the University's iconic Tiger Paw to space aboard a SpaceX Dragon spacecraft is, quite literally, "an out-of-this-world experience."

Cell & Microbiology Dec 10, 2021

New prime editing system inserts entire genes in human cells

Researchers at the Broad Institute of MIT and Harvard have developed a new version of prime editing that can install or swap out gene-sized DNA sequences. First developed in 2019, prime editing is a precise method of making ...

Biotechnology Dec 9, 2021

New biosensors shine a light on CRISPR gene editing

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

Bio & Medicine Dec 9, 2021

Nanotechnology for genome editing in multiple muscles simultaneously

Many intractable diseases are the result of a genetic mutation. Genome editing technology promises to correct the mutation and thus new treatments for patients. However, getting the technology to the cells that need the correction ...

Molecular & Computational biology Dec 3, 2021

Potential new gene editing tools uncovered

Few developments have rocked the biotechnology world or generated as much buzz as the discovery of CRISPR-Cas systems, a breakthrough in gene editing recognized in 2020 with a Nobel Prize. But these systems that naturally ...

Molecular & Computational biology Dec 3, 2021

The role of messenger RNA in DNA repair

An organism's genome could be compared to a complex system of instructions that allows it not only to develop, but also to carry out all the activities essential to its survival. To do this, this genome needs to be expressed ...

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