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Search results for drug discovery

Biochemistry Jan 11, 2023

Sweet discovery has potential for effective new virus and cancer drug treatments

Scientists have discovered sugar-based molecules can be used to block activity of a receptor in cells that are involved in the development a range of viral infections and cancer.

Biotechnology Jan 6, 2023

High-efficiency gene-editing tool used on fungi significantly improves pace of new drug discovery

As anyone who has ever attended a cocktail party can tell you, shedding inhibitions makes you more talkative and possibly more prone to divulging secrets. Fungi, it turns out, are no different from humans in this respect.

Biochemistry Jan 5, 2023

Natural product discoveries power drug discovery research

When Jeff Rudolf is explaining his work, he turns to the kitchen.

Biotechnology Jan 5, 2023

Solving a crucial bottleneck in drug discovery

Many existing antibiotics were derived from soil bacteria, which naturally produce these toxins to ward off competitors. But efforts to draw more therapeutics from the ground have hit a snag. Most species cannot be grown ...

Biochemistry Dec 15, 2022

How do you treat untreatable infections? Do what the microbes do

In a discovery with implications for the drug-resistance crisis, Princeton Engineering researchers have isolated a compound that kills bacteria that can cause incurable infections.

Biochemistry Dec 9, 2022

Surprise discovery set to improve drug development

A surprising discovery from the University of Virginia School of Medicine has torpedoed a key principle used in the development of new drugs to treat diseases. The finding could speed the drug-development process and help ...

Cell & Microbiology Dec 8, 2022

Discovery of a cellular uptake pathway for larger drug molecules

Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...

Materials Science Dec 6, 2022

Chemists develop reactions for the general synthesis of promising unexplored compounds

Chemists at Scripps Research have devised the first general method for synthesizing a family of compounds called 1,2,3,5-tetrazines, which hold great promise for making pharmaceuticals, biological probes and other chemical ...

Biochemistry Dec 6, 2022

Researchers compile ethnopharmacology of genus Veronicastrum

The genus Veronicastrum (Plantaginaceae) has about 20 species in the world with a distribution in eastern Asia and North America. Species in the genus Veronicastrum are beautiful perennial herbs with mostly alternate leaves, ...

Bio & Medicine Dec 1, 2022

Nanotech strategy shows promise for treating autoimmune disease

Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.

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