Biochemistry
Jan 5, 2023
Natural product discoveries power drug discovery research
When Jeff Rudolf is explaining his work, he turns to the kitchen.
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Search results for drug discovery
Biotechnology
Jan 5, 2023
Solving a crucial bottleneck in drug discovery
Many existing antibiotics were derived from soil bacteria, which naturally produce these toxins to ward off competitors. But efforts to draw more therapeutics from the ground have hit a snag. Most species cannot be grown ...
Biochemistry
Dec 15, 2022
How do you treat untreatable infections? Do what the microbes do
In a discovery with implications for the drug-resistance crisis, Princeton Engineering researchers have isolated a compound that kills bacteria that can cause incurable infections.
Biochemistry
Dec 9, 2022
Surprise discovery set to improve drug development
A surprising discovery from the University of Virginia School of Medicine has torpedoed a key principle used in the development of new drugs to treat diseases. The finding could speed the drug-development process and help ...
Cell & Microbiology
Dec 8, 2022
Discovery of a cellular uptake pathway for larger drug molecules
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...
Materials Science
Dec 6, 2022
Chemists develop reactions for the general synthesis of promising unexplored compounds
Chemists at Scripps Research have devised the first general method for synthesizing a family of compounds called 1,2,3,5-tetrazines, which hold great promise for making pharmaceuticals, biological probes and other chemical ...
Biochemistry
Dec 6, 2022
Researchers compile ethnopharmacology of genus Veronicastrum
The genus Veronicastrum (Plantaginaceae) has about 20 species in the world with a distribution in eastern Asia and North America. Species in the genus Veronicastrum are beautiful perennial herbs with mostly alternate leaves, ...
Bio & Medicine
Dec 1, 2022
Nanotech strategy shows promise for treating autoimmune disease
Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.
Biochemistry
Dec 1, 2022
Integrated platform promises to accelerate drug discovery process
Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.
Biochemistry
Nov 30, 2022
Researchers build powerful model for discovering new drugs
Researchers have developed a new computer framework that holds promise in the work to discover new drugs. Their framework uses an artificial intelligence method called a convolutional neural network to provide global information ...
