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Search results for therapeutic protein

Cell & Microbiology Mar 21, 2023

To ward off aging, stem cells must take out the trash

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells ...

Bio & Medicine Mar 20, 2023

Research team develops nanosensor capable of single-molecule precision in detecting biomarkers

While it is a popular hobby for many, fishing is also a pastime full of uncertainty. Each time you have something on the line, you can never be completely sure what type of fish you've hooked until you pull it out of the ...

Biochemistry Mar 16, 2023

Protein engineers navigate toward more targeted therapeutics

More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate ...

Bio & Medicine Mar 16, 2023

Antibody fragment-nanoparticle therapeutic eradicates gastric cancer, shows research

A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.

Molecular & Computational biology Mar 10, 2023

Enzyme ATE1 plays role in cellular stress response, opening door to new therapeutic targets

A new paper in Nature Communications illuminates how a previously poorly understood enzyme works in the cell. Many diseases are tied to chronic cellular stress, and UMBC's Aaron T. Smith and colleagues discovered that this ...

Cell & Microbiology Mar 8, 2023

Newly found protein complex plays a vital role in RNA protection and stability

Two proteins come together to protect and stabilize RNA as it carries muscle-forming code through the cell. Further understanding this RNA-stabilizing complex may have implications for influencing muscle recovery and disease ...

Bio & Medicine Mar 7, 2023

Brain tumor discovery paves way for new drug treatments

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and ...

Cell & Microbiology Mar 2, 2023

Researchers find mechanism that ensures correct DNA segregation in cell division

A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has uncovered a new mechanism that ensures correct DNA segregation in cell division, where improper ...

Biochemistry Mar 1, 2023

Guarding the genome: Researchers uncover full 3D structure of p53 protein

The tumor suppressor protein p53, known as "the guardian of the genome," protects the body's DNA from daily stress or long-term damage by triggering the cells to make repairs or to self-destruct. But mutations in the p53 ...

Biochemistry Feb 28, 2023

Effective method to avoid activating a cellular detoxification receptor to overcome drug resistance and toxicity

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance. The researchers made slight changes to a small molecule to reduce its metabolism and ...

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