How lactate defends cells under stress
Many people are familiar with lactate primarily from sports, where it is produced in muscle cells during physical exertion. However, the molecule could also play an important role in other cell types.
Many people are familiar with lactate primarily from sports, where it is produced in muscle cells during physical exertion. However, the molecule could also play an important role in other cell types.
Most bacteria cannot be cultured in the lab—and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath ...
Pathogens are becoming more and more resistant to antibiotics. With the goal of developing new therapeutic approaches to treat bacterial infections more effectively in the future, researchers at the Karlsruhe Institute of ...
Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions between phages and host bacteria ...
Taking medications on time, in the right dose and for the prescribed duration can be challenging for patients, and failure to do so comes with steep costs, causing 10% of hospitalizations and billions in avoidable spending ...
A new study from Aarhus University shows that our cells' ability to clean out old protein clumps, known as aggregates, also includes a—up till now unknown—partnership with an engine that breaks down bigger pieces into ...
Scientists from Immanuel Kant Baltic Federal University have found out that polysaccharides from microalgae bind proteins that are contained in the poison of lancehead snakes. When these proteins get into the human organism, ...
Imagine being able to flip a light switch to control disease pathways inside a living cell. A team of visionary researchers at the Texas A&M University Health Science Center (Texas A&M Health) is making this dream a reality ...
Investigators at Johns Hopkins Medicine report new evidence that the protein Piezo1 controls skin growth by detecting when skin is stretched and then coordinating the metabolic and immune changes necessary for growth. Experts ...
Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential housekeeping process, autophagy ...