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Search results for drug discovery

Molecular & Computational biology Nov 9, 2022

Pacemaker channel discovery could lead to better heart drugs

The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.

Biotechnology Nov 8, 2022

3D protein structure predictions made by AI could boost cancer research and drug discovery

In a living being, proteins make up roughly everything: from the molecular machines running every cell's metabolism, to the tip of your hair. Encoded in the DNA, a protein may be represented as a thread of hundreds of individual ...

Evolution Nov 3, 2022

Water was both a necessity and a barrier to early life on Earth. Microdroplets are a potential solution to this paradox

It's a paradox: Life needs water to survive, but a world full of water can't generate the biomolecules that would have been essential for early life. Or so researchers thought.

Materials Science Oct 28, 2022

Chiral drug-like building blocks by nickel-catalyzed enantioselective olefin cross-coupling

NUS chemists have developed an effective method to access enantioenriched drug-like compounds through multicomponent olefin cross-coupling using chiral nickel-based catalysts.

Biochemistry Oct 26, 2022

Cancer drug could potentially be used against malaria

A cancer drug currently in clinical trials has shown the potential to protect from, cure, and prevent transmission of malaria. The breakthrough finding by an international team that includes researchers at Penn State offers ...

Biochemistry Oct 25, 2022

New enzyme inhibitor shows promise for treating cancers, autoimmune diseases

Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases.

Cell & Microbiology Oct 24, 2022

Analyzing diverse data types can accelerate drug discovery, study says

A new paper in Cell Systems explores the importance of using multiple data types in drug discovery. The paper screens more than 1,000 drugs tested in six doses and demonstrates that gene expression and cell morphology provide ...

Ecology Oct 19, 2022

Mushroom that grows on insects could help develop new anti-viral medications and cancer drugs

The Cordyceps mushroom is best known for its gruesome eating habits: famously, its spores infect insects and kill them, growing into fully-fledged fruiting bodies that sprout from the insects' flesh. But Cordyceps also has ...

Biochemistry Oct 17, 2022

A new AI model can accurately predict human response to novel drug compounds

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upward of a billion dollars. A research team at the CUNY Graduate ...

Biochemistry Oct 13, 2022

Drug discovery method identifies naturally occurring metabolite that converts 'bad' fat to 'good' fat

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes—or, as a new discovery ...

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