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Cell & Microbiology Mar 4, 2019

Diabetes impairs multipotent stromal cell antibacterial activity

A new study reveals that the multipotent stromal cells (MSCs) of persons with diabetes have diminished capacity to fight off bacterial infection, providing new understanding into the basis of diabetes-associated immune dysfunction. ...

Biotechnology Feb 28, 2019

Turning them on, turning them off—how to control stem cells

Scientists at the University of Bath have identified how a mutant gene in fish is involved in controlling stem cells.

Materials Science Feb 27, 2019

Turning stem cells into bone with nanoclay-reinforced hydrogel

Assistant Professor Alireza Dolatshahi-Pirouz and colleagues have developed a hydrogel that combines synthetic materials with living cells, and can turn stem cells into bone without adding external growth or differentiation ...

Cell & Microbiology Feb 21, 2019

New mechanisms regulating neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. Scientists at Helmholtz Zentrum München and Ludwig Maximilian University of Munich (LMU) have discovered that the protein ...

Bio & Medicine Feb 13, 2019

What happens to magnetic nanoparticles in cells?

Although magnetic nanoparticles are being used more and more in cell imaging and tissue bioengineering, what happens to them within stem cells in the long term remained undocumented. Researchers from CNRS, the Sorbonne Université, ...

Biotechnology Feb 11, 2019

Injectable sponge-like gel enhances the quantity and quality of T-cells

Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion ...

Evolution Feb 8, 2019

Chimpanzee 'mini-brains' hint at secrets of human evolution

At some point during human evolution, a handful of genetic changes triggered a dramatic threefold expansion of the brain's neocortex, the wrinkly outermost layer of brain tissue responsible for everything from language to ...

Cell & Microbiology Jan 25, 2019

Researchers re-create retinal microenvironment in a dish with human stem cells

IUPUI biologists, growing human pluripotent stem cell-derived retinal ganglion cells in the lab, have developed a way to create more-mature models that better mimic the environment in the human retina. By introducing hPSC-RGCs ...

Cell & Microbiology Jan 16, 2019

How stem cells self-organize in the developing embryo

Embryonic development is a process of profound physical transformation, one that has challenged researchers for centuries. How do genes and molecules control forces and tissue stiffness to orchestrate the emergence of form ...

Cell & Microbiology Jan 14, 2019

Stem cells regulate their fate by altering their stiffness

In adults, mesenchymal stems cells (MSCs) are primarily found in bone marrow and they play a vital role in repair of damaged organs. The transformation of a single MSC into complex tissue like cartilage and bone starts with ...

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