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Molecular & Computational biology Jul 21, 2025

Novel method of targeting disordered proteins could herald a new era for medicine

Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought inaccessible to drug development, ...

Cell & Microbiology Jul 21, 2025

How cells repair toxic DNA damage linked to cancer and premature aging

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, ...

Molecular & Computational biology Jul 18, 2025

New AI-powered method accelerates protein simulations and reveals complex folding dynamics

An international team led by Einstein Professor Cecilia Clementi in the Department of Âé¶¹ÒùÔºics at Freie Universität Berlin has introduced CGSchNet, a machine-learned coarse-grained (CG) model that can accurately and efficiently ...

Analytical Chemistry Jul 18, 2025

Chemists unlock elusive carbenes, paving the way for next-generation medicines

Chemists have developed a novel way to generate a variety of highly useful chemical building blocks by harnessing metal carbenes, suggests new research.

Molecular & Computational biology Jul 17, 2025

Secrets of the dark genome could spark new drug discoveries

Since the Human Genome Project first produced the genetic instructions for a human being by sequencing DNA 22 years ago, scientists have been focused on roughly 2% of the genome-producing proteins.

Cell & Microbiology Jul 16, 2025

Research reveals how the superfungus Candida auris withstands antifungal treatment

A groundbreaking study from Michigan State University (MSU), published in Nature Communications, reveals how the multidrug-resistant superfungus Candida auris uniquely reconstructs its cell wall to survive antifungal treatments. ...

Cell & Microbiology Jul 16, 2025

Amino acids play a key role in how cells respond to drugs

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure.

Molecular & Computational biology Jul 15, 2025

Study reveals hidden enzyme redundancy in staph bacteria's survival pathways

In the ongoing battle against antibiotic-resistant bacteria, MSU researchers have made a discovery that could reshape how we target deadly pathogens like staph infections.

Biotechnology Jul 14, 2025

AI finds hundreds of potential antibiotics in snake and spider venom

Snake, scorpion, and spider venom are most frequently associated with poisonous bites, but with the help of artificial intelligence, they might be able to help fight antibiotic resistance, which contributes to more than one ...

Molecular & Computational biology Jul 14, 2025

Emerging viral threats combated by a potent new dual lipid kinase inhibitor

Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, provides ...

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