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Search results for CRISPR-Cas9

Biotechnology Nov 7, 2024

Plant engineering method promises to dramatically improve biofuel and bioproduct development

The ability to genetically engineer plants is largely thanks to a microscopic helper: a bacterium called Agrobacterium tumefaciens. Agrobacterium in the wild causes damaging tumors in flowering plants, including some economically ...

Biotechnology Nov 7, 2024

RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential—not 'junk'

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of ...

Ecology Nov 5, 2024

Deaf male mosquitoes don't mate, researchers discover

Romance is a complex affair in humans. There's personality, appearance, seduction, all manner of physical and social cues. Mosquitoes are much more blunt. Mating occurs for a few seconds in midair. And all it takes to woo ...

Cell & Microbiology Nov 4, 2024

Newly described anti-viral defense system in bacteria aborts infection by chemically altering mRNA

Like humans and other complex multicellular organisms, single-celled bacteria can fall ill and fight off viral infections. A bacterial virus is caused by a bacteriophage, or, more simply, phage, which is one of the most ubiquitous ...

Ecology Nov 1, 2024

Honeybee gene specifies collective behavior, research shows

Researchers at Heinrich Heine University Düsseldorf (HHU) are collaborating with colleagues from Frankfurt/Main, Oxford and Würzburg to investigate how the complex, cooperative behavior of honeybees (Apis mellifera) is ...

Cell & Microbiology Oct 28, 2024

CRISPR-Cas10 can flood virally infected bacteria with toxic molecules, researchers discover

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA with elegant precision.

Biotechnology Oct 28, 2024

Researchers discover underlying mechanisms that make CRISPR an effective gene editing tool

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how this tool works and avoids ...

Cell & Microbiology Oct 14, 2024

Brazilian study identifies potential targets for treatment of visceral leishmaniasis

Researchers at the Federal University of São Carlos (UFSCar), the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil have characterized for the first time a class of proteins present ...

Biotechnology Oct 2, 2024

Filament structure found to activate and regulate CRISPR-Cas 'protein scissors'

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins ...

Biotechnology Oct 1, 2024

Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows promise for gene editing

Scientists at St. Jude Children's Research Hospital have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors.

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