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Search results for genome editing

Plants & Animals Jul 1, 2025

New 'gene gun' design boosts efficiency of plant genetic modification

Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.

Biotechnology Jul 1, 2025

Web-based tool improves CRISPR accuracy by identifying off-target effects across genetic variations

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause harmful mutations and ...

Biochemistry Jun 25, 2025

Soil bacterium's diverse genes yield two new natural product families with antifungal effects

A study by an interdisciplinary research team shows how a soil bacterium can become a source of inspiration in the search for new active substances. Genomic analyses of the plant pathogen Pseudomonas syringae shed light on ...

Biotechnology Jun 25, 2025

Mice born of two dads reveal hidden details of mammalian reproduction

Researchers at Shanghai Jiao Tong University have produced fertile adult mice from embryos constructed entirely with male genetic material. Mice carrying only paternal DNA developed into fertile adults following precision ...

Molecular & Computational biology Jun 23, 2025

Why regulations in plant gene editing are a must

While some scientists argue that agricultural gene editing regulations are overly restrictive, a new paper from the University of Adelaide emphasizes the importance of clear regulations to ensure that new technologies are ...

Bio & Medicine Jun 18, 2025

Gene-editing nanoparticle system targets multiple organs simultaneously

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), ...

Molecular & Computational biology Jun 16, 2025

RNA has newly identified role: Repairing serious DNA damage to maintain the genome

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double helix.

Cell & Microbiology Jun 12, 2025

Genetically modified T. kivui gains ability to metabolize carbon monoxide

Genetic changes can occur naturally through evolution or can be initiated with the help of genetic engineering. The bacterium Thermoanaerobacter kivui (T. kivui) was manipulated by a research team led by Stefan Pflügl from ...

Biotechnology Jun 11, 2025

Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly enhance the low efficiency ...

Biotechnology Jun 10, 2025

Genome engineers expand the reach and precision of human gene editing

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing technologies can alter or delete ...

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