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Search results for CRISPR-Cas9

Cell & Microbiology Sep 4, 2024

Scientists uncover diverse marine microbes with potential for new antibiotics and plastic breakdown

New research shows how oceans can be used to help address major challenges such as the shortage of antimicrobial medicines, solutions for plastic pollution and novel enzymes for genome editing.

Bio & Medicine Sep 4, 2024

Team identifies a 'forcefield-like' defense system in solid tumors and the genetic elements that can switch it off

The tumor microenvironment—an ad hoc, messy amalgamation of signaling molecules, immune cells, fibroblasts, blood vessels, and the extracellular matrix—acts like a "powerful security system that protects solid tumors ...

Biotechnology Sep 3, 2024

Breaking boundaries: PAM-less genome editing in soybean

CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations ...

Cell & Microbiology Aug 16, 2024

Newly discovered mechanism for propagation of flaviviruses reveals potential therapeutic target

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and tick-borne encephalitis virus, are significant arthropod-borne pathogens. ...

Molecular & Computational biology Aug 9, 2024

Unlocking the potential of rapeseed: CRISPR edits for hybrid efficiency

Hybrid production in rapeseed faces several significant challenges, primarily due to the complexities and limitations of current male sterility systems. Traditional methods often involve intricate management processes and ...

Plants & Animals Aug 8, 2024

Editing for resilience: CRISPR/Cas9 boosts potato stress resistance

Scientists have made a significant breakthrough in agricultural biotechnology by using CRISPR/Cas9 to edit the potato genome, resulting in plants with increased resistance to both biotic and abiotic stresses. This innovation ...

Plants & Animals Aug 8, 2024

Smooth sailing for eggplant: Breakthrough in understanding prickle formation

Scientists have discovered the gene responsible for prickles in eggplants, a trait that complicates farming. Using advanced genetic techniques, they identified the Prickly Eggplant (PE) gene on chromosome 6 and pinpointed ...

Plants & Animals Jul 30, 2024

Stem cell harmony: How solanaceae plants maintain homeostasis through receptor compensation

A pivotal study sheds light on the evolutionary conservation of stem cell homeostasis in Solanaceae, revealing how receptor compensation mechanisms ensure the continuous and orderly formation of plant organs. This research ...

Molecular & Computational biology Jul 30, 2024

Precise genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This ...

Plants & Animals Jul 30, 2024

Fruitful innovation: Transforming watermelon genetics with advanced base editors

The development of new adenine base editors (ABE) and adenine-to-thymine/guanine base editors (AKBE) is transforming watermelon genetic engineering. These innovative tools enable precise A:T-to-G and A:T-to-T base substitutions, ...

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