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October 15, 2024

Novel thermosensitive hydrogel-based fluorescence probe offers fast detection of nitrite

Schematic representation of Au-NCs/LCG-P407 fluorescent hydrogel for the detection of NO₂⁻. Credit: Journal of Hazardous Materials (2024). DOI: 10.1016/j.jhazmat.2024.135471
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Schematic representation of Au-NCs/LCG-P407 fluorescent hydrogel for the detection of NO₂⁻. Credit: Journal of Hazardous Materials (2024). DOI: 10.1016/j.jhazmat.2024.135471

Nitrite (NO₂⁻) is commonly used as a food additive, but when ingested, it can harm the body's oxygen transport system. The World Health Organization limits NO₂⁻ to 1.0 mg/L in drinking water and 30 mg/kg in meat products. However, current nitrite detection methods are often complicated.

Recently, a team of researchers led by Prof. Jiang Changlong from Institute of Solid State 鶹Ժics, the Hefei Institutes of 鶹Ժical Sciences of the Chinese Academy of Sciences, developed a novel thermosensitive hydrogel-based fluorescence probe for real-time visualization and detection of nitrite.

They the progress in Journal of Hazardous Materials.

"With this probe and a smartphone, the nitrite data is available at a glance," said Dr. Li Lingfei, a member of the team.

In this research, the functionalized thermosensitive hydrogel doped with was designed to make it easier to get information of NO₂⁻. Gold nanoclusters (Au NCs) and carbon-based dots were added into the hydrogel's multi-layered structure, which was made from P407, lignin, and cellulose. This created a material with special fluorescence properties and strong stability. The interconnected P407, lignin, and cellulose gave the hydrogel an excellent porous structure.

This novel Au NCs/LCG-P407 fluorescent hydrogel has been designed with the objective of optimizing portable and efficient device strategies. It provides a basis for further development of sensing platforms for the detection of environmental and in food safety.

The hydrogel sensor can also be paired with a to visually measure NO₂⁻ in water, making detection easier and more practical. This research marks an advancement in hydrogel applications and highlights its potential to enhance monitoring systems, according to the team.

More information: Lingfei Li et al, Multi-deformable interpenetrating network thermosensitive hydrogel fluorescent device for real-time and visual detection of nitrite, Journal of Hazardous Materials (2024).

Journal information: Journal of Hazardous Materials

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